TPS6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TPS6_ARATH
• UniProt AC: Q94AH8
• Protein Name: Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6
• Gene Name: TPS6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 860
• Protein Description: Regulates plant architecture, shape of epidermal pavement cells and branching of trichomes..
• Protein Sequence: MVSRSYSNLLELASGDSPTFGRMNRQIPRIMAVAGIMSNIDNDSKDTDLSPKDRIIIVANELPIRAQRRVDGNGSGSSSSSTCCSKGWNFSWDENSLLLQLKDGLGDEAIEVIYVGCLKEEIPLNEQEEVYQILLESFKCVPTFLPLDLYTRYYHGFCKQQLWPLFHYMLPLSPDLGGRFDRTLWQAYVSVNKIFADRIMEVINPEDDFVWIHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYKTLPIREELLRALLNSDLIGFHTFDYARHFLSCCSRMLGLTYESKRGYIGLEYYGRTVSIKILPVGIHMGQLQSVLSLPETERKVGELIERYGRKGRTMLLGVDDMDIFKGITLKLLAMEQLLMQHPEWQGKVVLVQIANPARGKGKDVKEMQAETYSTVKRINETFGRPGYDPIVLIDAPLKFYERVAYYVVAECCLVTAVRDGMNLIPYEYIVSRQGNEKLDKILKLEANNRNKKSMLVVSEFIGCSPSLSGAIRVNPWNVDAVADAMDSALEVAEPEKQLRHEKHYKYVSTHDVGYWARSFLQDLERSCGEHGRRRCWGIGFGLSFRVVALDQSFRKLSMEHIVSAYKRTKTRAILLDYDDTLMPQGSIDKRPSSKSIDILNTLCRDKGNLVFIVSAKSRETLSDWFSPCEKLGIAAEHGYFLRLRKAVEWENCVAAVDCSWKQIAEPVMELYTETTDGSTIEDKETALVWSYEDADPDFGSCQAKELLDHLESVLANEPVTVKRGQNYVEVKPQGVSKGLIARRMLSMMQERGTLPEFVLCIGDDRSDEDMFEVICSSTEGPSIAPRAEIFACTVGQKPSKAKYYLDDTTEIVRLMHGLASVTDQITPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MVSRSYSNLLEL ---CCCCCHHHHHHH	25.96	30291188
6	Phosphorylation	--MVSRSYSNLLELA --CCCCCHHHHHHHH	10.64	23572148
7	Phosphorylation	-MVSRSYSNLLELAS -CCCCCHHHHHHHHC	23.42	30407730
14	Phosphorylation	SNLLELASGDSPTFG HHHHHHHCCCCCCHH	56.61	30407730
17	Phosphorylation	LELASGDSPTFGRMN HHHHCCCCCCHHHHH	29.39	30291188
19	Phosphorylation	LASGDSPTFGRMNRQ HHCCCCCCHHHHHHH	42.55	30407730
584	Phosphorylation	RVVALDQSFRKLSME EEEEECHHHHHHCHH	27.04	25561503
589	Phosphorylation	DQSFRKLSMEHIVSA CHHHHHHCHHHHHHH	25.76	19376835

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TPS6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TPS6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TPS6_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of TPS6_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-589, AND MASSSPECTROMETRY.
PubMed: 19376835