dbPTM

TPIS_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TPIS_ARATH
UniProt AC	P48491
Protein Name	Triosephosphate isomerase, cytosolic
Gene Name	CTIMC
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	254
Subcellular Localization	Cytoplasm . Mitochondrion .
Protein Description
Protein Sequence	MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDIIKAAEVKKSA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
106	Phosphorylation	RRAILNESSEFVGDK HHHHHCCCCCHHHHH	33.81	23111157
127	S-nitrosylation	QGLKVIACVGETLEE HCCEEEEEEECCHHH	2.51	22115780
131	Phosphorylation	VIACVGETLEEREAG EEEEEECCHHHHHCC	33.28	22092075
139	Phosphorylation	LEEREAGSTMDVVAA HHHHHCCCCHHHHHH	27.83	22092075
140	Phosphorylation	EEREAGSTMDVVAAQ HHHHCCCCHHHHHHH	19.24	29797451
141	Sulfoxidation	EREAGSTMDVVAAQT HHHCCCCHHHHHHHH	3.84	23289948
178	Phosphorylation	IGTGKVASPAQAQEV ECCCCCCCHHHHHHH	24.61	22092075
212	Phosphorylation	TRIIYGGSVNGGNCK EEEEECCCCCCCCCC	14.19	30291188
218	S-nitrosylation	GSVNGGNCKELGGQA CCCCCCCCCCCCCCC	4.02	22115780

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TPIS_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TPIS_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TPIS_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TPIS_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TPIS_ARATH

Related Literatures of Post-Translational Modification