dbPTM

TOR2A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TOR2A_HUMAN
UniProt AC	Q5JU69
Protein Name	Torsin-2A
Gene Name	TOR2A
Organism	Homo sapiens (Human).
Sequence Length	321
Subcellular Localization	Endoplasmic reticulum lumen.
Protein Description
Protein Sequence	MAAATRGCRPWGSLLGLLGLVSAAAAAWDLASLRCTLGAFCECDFRPDLPGLECDLAQHLAGQHLAKALVVKALKAFVRDPAPTKPLVLSLHGWTGTGKSYVSSLLAHYLFQGGLRSPRVHHFSPVLHFPHPSHIERYKKDLKSWVQGNLTACGRSLFLFDEMDKMPPGLMEVLRPFLGSSWVVYGTNYRKAIFIFISNTGGKQINQVALEAWRSRRDREEILLQELEPVISRAVLDNPHHGFSNSGIMEERLLDAVVPFLPLQRHHVRHCVLNELAQLGLEPRDEVVQAVLDSTTFFPEDEQLFSSNGCKTVASRIAFFL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MAAATRGCRPWG ---CCCCCCCCCHHH	23.91	24043423
13	Phosphorylation	RGCRPWGSLLGLLGL CCCCHHHHHHHHHHH	19.29	24043423
22	Phosphorylation	LGLLGLVSAAAAAWD HHHHHHHHHHHHHHH	19.75	24043423
32	Phosphorylation	AAAWDLASLRCTLGA HHHHHHHHHHHCHHH	24.52	24719451
117	Phosphorylation	LFQGGLRSPRVHHFS HHHCCCCCCCCCCCC	23.31	17081983
149	N-linked_Glycosylation	LKSWVQGNLTACGRS HHHHHHCCCCHHCCE	19.68	UniProtKB CARBOHYD
232	Phosphorylation	QELEPVISRAVLDNP HHHHHHHHHHHHCCC	17.89	-
244	Phosphorylation	DNPHHGFSNSGIMEE CCCCCCCCCCCHHHH	34.38	-
246	Phosphorylation	PHHGFSNSGIMEERL CCCCCCCCCHHHHHH	28.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TOR2A_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TOR2A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TOR2A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TOR2A_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TOR2A_HUMAN

Related Literatures of Post-Translational Modification