TOM40_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TOM40_MOUSE
• UniProt AC: Q9QYA2
• Protein Name: Mitochondrial import receptor subunit TOM40 homolog
• Gene Name: Tomm40
• Organism: Mus musculus (Mouse).
• Sequence Length: 361
• Subcellular Localization: Mitochondrion outer membrane ; Multi-pass membrane protein .
• Protein Description: Channel-forming protein essential for import of protein precursors into mitochondria..
• Protein Sequence: MGNVLAASSPPAGPPPPPTPSLVGLPPPPPSPPGFTLPPLGGGLGTGSSTGRGSERTPGAAASGAAAASEDGSCGCLPNPGTFEECHRKCKELFPVQMEGVKLTVNKGLSNRFQVTHTVALGTIGESNYHFGVTYVGTKQLSPTEAFPVLVGDMDNSGSLNAQVIHQLSPGLRSKMAIQTQQSKFVNWQVDGEYRGSDFTAAVTLGNPDVLVGSGILVAHYLQSITPCLALGGELVYHRRPGEEGTVMSLAGKYTLNNWLATVTLGQAGMHATYYHKASDQLQVGVEFEASTRMQDTSASFGYQLDLPKANFLFKGSVNSNWIVGATLEKKLPPLPLTLSLCAFLNHRKNKFLCGFGLTIG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	Phosphorylation	ASGAAAASEDGSCGC CCCCCCCCCCCCCCC	31.34	-
76	S-palmitoylation	SEDGSCGCLPNPGTF CCCCCCCCCCCCCCH	7.19	28680068
89	Ubiquitination	TFEECHRKCKELFPV CHHHHHHHHHHHCCC	26.45	-
91	Ubiquitination	EECHRKCKELFPVQM HHHHHHHHHHCCCCE	61.56	22790023
102	Ubiquitination	PVQMEGVKLTVNKGL CCCEEEEEEEECCCC	49.66	22790023
107	Ubiquitination	GVKLTVNKGLSNRFQ EEEEEECCCCCCCCE	57.82	22790023
142	Phosphorylation	YVGTKQLSPTEAFPV EEECCCCCCCCCCCE	27.55	23984901
144	Phosphorylation	GTKQLSPTEAFPVLV ECCCCCCCCCCCEEE	36.25	23984901
157	Phosphorylation	LVGDMDNSGSLNAQV EEECCCCCCCCCHHH	26.04	26745281
159	Phosphorylation	GDMDNSGSLNAQVIH ECCCCCCCCCHHHHH	20.47	26745281
169	Phosphorylation	AQVIHQLSPGLRSKM HHHHHHHCHHHHHCE	15.45	29514104
175	Ubiquitination	LSPGLRSKMAIQTQQ HCHHHHHCEEEEECH	26.39	22790023
183	Phosphorylation	MAIQTQQSKFVNWQV EEEEECHHHCCCEEE	20.46	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TOM40_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TOM40_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TOM40_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TOM40_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.