TOM1_MOUSE - dbPTM
TOM1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TOM1_MOUSE
UniProt AC O88746
Protein Name Target of Myb protein 1
Gene Name Tom1
Organism Mus musculus (Mouse).
Sequence Length 492
Subcellular Localization Cytoplasm . Membrane
Peripheral membrane protein .
Protein Description May be involved in intracellular trafficking. Probable association with membranes..
Protein Sequence MDFLLGNPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDAFRAVKKRIMGNKNFHEVMLALTVLETCVKNCGHRFHVLVANQDFVENVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVAVYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETPSRQNSVSSNTSQRGDLSQHATPLPTPAVLPGDSPITPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQVEPADLELLQELNRTCRAMQQRILELIPRISNEQLTEELLMINDNLNNVFLRHERFERFRTGQTAKASSEAELATDLIDMGPDPAATNNLSSQLAGMNLGSRSVRAGLQSLETSGHLEDDFDMFALTRGSSLADQRKGVKYEAPQTTDGLAGALDARQQSTGAIPATQARIMEDIEQWLSTDVGNSAEEPSGVTSEEFDKFLEERAKAADRLPNLASPSAEGPPRPSPGTAPRRKTQEKDDDMLFAL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MDFLLGNP
-------CCCCCCCC		8.09-
11PhosphorylationLLGNPFSSPVGQRIE
CCCCCCCCCCHHHHH		24.80-
106UbiquitinationLVRTILPKNNPPTIV
EHHHHCCCCCCCCCH		66.95-
154PhosphorylationKGLEFPMTDLDMLSP
CCCCCCCCCHHHCCC		33.3824925903
160PhosphorylationMTDLDMLSPIHTPQR
CCCHHHCCCCCCCCC		18.3825521595
164PhosphorylationDMLSPIHTPQRTVFN
HHCCCCCCCCCCCCC		23.1024925903
168PhosphorylationPIHTPQRTVFNSETP
CCCCCCCCCCCCCCC		24.9726643407
172PhosphorylationPQRTVFNSETPSRQN
CCCCCCCCCCCCCCC		31.2329899451
174PhosphorylationRTVFNSETPSRQNSV
CCCCCCCCCCCCCCC		26.7827742792
176PhosphorylationVFNSETPSRQNSVSS
CCCCCCCCCCCCCCC		54.6525521595
180PhosphorylationETPSRQNSVSSNTSQ
CCCCCCCCCCCCCCC		18.2925521595
182PhosphorylationPSRQNSVSSNTSQRG
CCCCCCCCCCCCCCC		20.0727742792
183PhosphorylationSRQNSVSSNTSQRGD
CCCCCCCCCCCCCCC		41.8123737553
185PhosphorylationQNSVSSNTSQRGDLS
CCCCCCCCCCCCCCC		28.3427742792
186PhosphorylationNSVSSNTSQRGDLSQ
CCCCCCCCCCCCCCC		23.3327742792
192PhosphorylationTSQRGDLSQHATPLP
CCCCCCCCCCCCCCC		25.3525159016
196PhosphorylationGDLSQHATPLPTPAV
CCCCCCCCCCCCCCC		24.1925159016
200PhosphorylationQHATPLPTPAVLPGD
CCCCCCCCCCCCCCC		31.4025159016
208PhosphorylationPAVLPGDSPITPTPE
CCCCCCCCCCCCCHH		24.9026824392
211PhosphorylationLPGDSPITPTPEQIG
CCCCCCCCCCHHHHH		25.2122942356
213PhosphorylationGDSPITPTPEQIGKL
CCCCCCCCHHHHHHH		30.7025159016
311UbiquitinationFRTGQTAKASSEAEL
HHCCCCCCCCCHHHH		52.79-
313PhosphorylationTGQTAKASSEAELAT
CCCCCCCCCHHHHHH		28.1823737553
314PhosphorylationGQTAKASSEAELATD
CCCCCCCCHHHHHHH		45.7623737553
320PhosphorylationSSEAELATDLIDMGP
CCHHHHHHHHHHCCC		43.9225293948
332PhosphorylationMGPDPAATNNLSSQL
CCCCHHHHCCHHHHH		27.0925293948
337PhosphorylationAATNNLSSQLAGMNL
HHHCCHHHHHHCCCC		32.1728059163
355PhosphorylationSVRAGLQSLETSGHL
HHHHHHHHHHHCCCC		32.9626239621
358PhosphorylationAGLQSLETSGHLEDD
HHHHHHHHCCCCCCC		45.3526239621
359PhosphorylationGLQSLETSGHLEDDF
HHHHHHHCCCCCCCC		18.1626239621
375PhosphorylationMFALTRGSSLADQRK
EEEECCCCCHHHHCC		20.9123737553
376PhosphorylationFALTRGSSLADQRKG
EEECCCCCHHHHCCC		30.3330352176
382UbiquitinationSSLADQRKGVKYEAP
CCHHHHCCCCCCCCC		63.52-
385UbiquitinationADQRKGVKYEAPQTT
HHHCCCCCCCCCCCC		46.14-
386PhosphorylationDQRKGVKYEAPQTTD
HHCCCCCCCCCCCCC		18.2122817900
405PhosphorylationALDARQQSTGAIPAT
HHCHHHHHCCCCCHH		22.0725521595
406PhosphorylationLDARQQSTGAIPATQ
HCHHHHHCCCCCHHH		26.7125521595
462PhosphorylationDRLPNLASPSAEGPP
HHCCCCCCCCCCCCC		23.6625521595
464PhosphorylationLPNLASPSAEGPPRP
CCCCCCCCCCCCCCC		36.1424925903
472PhosphorylationAEGPPRPSPGTAPRR
CCCCCCCCCCCCCCC		36.9225521595
475PhosphorylationPPRPSPGTAPRRKTQ
CCCCCCCCCCCCCCC		36.5524925903
481PhosphorylationGTAPRRKTQEKDDDM
CCCCCCCCCCCCCCC		39.9025338131
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TOM1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TOM1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TOM1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TOM1_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TOM1_MOUSE

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-174; SER-176 ANDSER-180, AND MASS SPECTROMETRY.

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