TNNC1_RABIT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TNNC1_RABIT
• UniProt AC: P02591
• Protein Name: Troponin C, slow skeletal and cardiac muscles
• Gene Name: TNNC1
• Organism: Oryctolagus cuniculus (Rabbit).
• Sequence Length: 161
• Protein Description: Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments..
• Protein Sequence: MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDDIYKAA -------CHHHHHHH	10.62	7358047
98	Phosphorylation	GKSEEELSDLFRMFD CCCHHHHHHHHHHHH	35.23	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TNNC1_RABIT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TNNC1_RABIT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TNNC1_RABIT !!

Protein-Protein Interaction

Oops, there are no PPI records of TNNC1_RABIT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.