| UniProt ID | TNFL9_MOUSE | |
|---|---|---|
| UniProt AC | P41274 | |
| Protein Name | Tumor necrosis factor ligand superfamily member 9 | |
| Gene Name | Tnfsf9 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 309 | |
| Subcellular Localization |
Membrane Single-pass type II membrane protein. |
|
| Protein Description | Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.. | |
| Protein Sequence | MDQHTLDVEDTADARHPAGTSCPSDAALLRDTGLLADAALLSDTVRPTNAALPTDAAYPAVNVRDREAAWPPALNFCSRHPKLYGLVALVLLLLIAACVPIFTRTEPRPALTITTSPNLGTRENNADQVTPVSHIGCPNTTQQGSPVFAKLLAKNQASLCNTTLNWHSQDGAGSSYLSQGLRYEEDKKELVVDSPGLYYVFLELKLSPTFTNTGHKVQGWVSLVLQAKPQVDDFDNLALTVELFPCSMENKLVDRSWSQLLLLKAGHRLSVGLRAYLHGAQDAYRDWELSYPNTTSFGLFLVKPDNPWE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 58 | Phosphorylation | ALPTDAAYPAVNVRD CCCCCCCCCCCCCCC | 8.08 | 20116462 | |
| 139 | N-linked_Glycosylation | VSHIGCPNTTQQGSP CCCCCCCCCCCCCCH | 60.89 | - | |
| 158 | Phosphorylation | LLAKNQASLCNTTLN HHHHCCHHHCCCEEE | 24.56 | 25777480 | |
| 161 | N-linked_Glycosylation | KNQASLCNTTLNWHS HCCHHHCCCEEECCC | 41.20 | - | |
| 162 | Phosphorylation | NQASLCNTTLNWHSQ CCHHHCCCEEECCCC | 31.50 | 25777480 | |
| 163 | Phosphorylation | QASLCNTTLNWHSQD CHHHCCCEEECCCCC | 12.24 | 25777480 | |
| 168 | Phosphorylation | NTTLNWHSQDGAGSS CCEEECCCCCCCCHH | 22.91 | 25777480 | |
| 174 | Phosphorylation | HSQDGAGSSYLSQGL CCCCCCCHHHHHCCC | 18.44 | 25777480 | |
| 175 | Phosphorylation | SQDGAGSSYLSQGLR CCCCCCHHHHHCCCC | 29.22 | 25777480 | |
| 176 | Phosphorylation | QDGAGSSYLSQGLRY CCCCCHHHHHCCCCC | 16.45 | 25777480 | |
| 178 | Phosphorylation | GAGSSYLSQGLRYEE CCCHHHHHCCCCCCC | 17.61 | 25777480 | |
| 293 | N-linked_Glycosylation | DWELSYPNTTSFGLF CCCCCCCCCCEEEEE | 47.99 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TNFL9_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TNFL9_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TNFL9_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TNFL9_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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