TMX2_MOUSE - dbPTM
TMX2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TMX2_MOUSE
UniProt AC Q9D710
Protein Name Thioredoxin-related transmembrane protein 2
Gene Name Tmx2
Organism Mus musculus (Mouse).
Sequence Length 295
Subcellular Localization Membrane
Single-pass type I membrane protein .
Protein Description
Protein Sequence MAVLAPLIALVYSVPRLSRWLARPYCLLSALLSIAFLLVRKLPPICNGLPTQREDGNPCDFDWREVEILMFLSAIVMMKNRRSITVEQHVGNIFMFSKVANAILFFRLDIRMGLLYLTLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCSGLNFGKVDVGRYTDVSTRYKVSTSPLTRQLPTLILFQGGKEVIRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKHSKGGDMSEEKPVDPAPTTVPDGENKKDK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
186S-nitrosocysteineDLSLKYNCSGLNFGK
EEEEEEECCCCCCCE
2.87-
186S-nitrosylationDLSLKYNCSGLNFGK
EEEEEEECCCCCCCE
2.8721278135
186S-palmitoylationDLSLKYNCSGLNFGK
EEEEEEECCCCCCCE
2.8728526873
187PhosphorylationLSLKYNCSGLNFGKV
EEEEEECCCCCCCEE
42.5522817900
193UbiquitinationCSGLNFGKVDVGRYT
CCCCCCCEEEECEEC
30.9922790023
207UbiquitinationTDVSTRYKVSTSPLT
CCCCCEEEECCCCCH
26.8122790023
209PhosphorylationVSTRYKVSTSPLTRQ
CCCEEEECCCCCHHC
21.0029472430
210PhosphorylationSTRYKVSTSPLTRQL
CCEEEECCCCCHHCC
37.0325159016
211PhosphorylationTRYKVSTSPLTRQLP
CEEEECCCCCHHCCC
15.4825159016
214PhosphorylationKVSTSPLTRQLPTLI
EECCCCCHHCCCEEE
21.5425159016
227UbiquitinationLILFQGGKEVIRRPQ
EEEEECCEEEEECCC
56.4822790023
243PhosphorylationDKKGRAVSWTFSEEN
CCCCCCCEEECCHHH
21.2926824392
245PhosphorylationKGRAVSWTFSEENVI
CCCCCEEECCHHHHH
15.1321659604
274PhosphorylationHSKGGDMSEEKPVDP
HCCCCCCCCCCCCCC
47.5523684622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TMX2_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TMX2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TMX2_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TMX2_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TMX2_MOUSE

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Related Literatures of Post-Translational Modification

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