TMTC3_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMTC3_DROME
• UniProt AC: Q7K4B6
• Protein Name: Transmembrane and TPR repeat-containing protein CG4050
• Gene Name: CG4050
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 926
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MSTNPNPGIHQYAPSTLPREREREGATNSPQRNLLEFLCICVACIVCYYNSTQCGLVFDDISAIRDNKDLRPHTPLINVFLNDFWGTPMRKEQSHKSYRPLTVLTFRFNYLLHALEPFGYHLVNLLLHLSVCLLWRRVCRLLLRQCAASGSNAISAPSSSSVSQLNTCAFVASLLFAVHPVHTEAVTGVVGRAELLSSICFLAAFLSYAKSVGDSGCPRRTNWLTLFGCFGSCLLASMLCKEQGITIAGICVVYELFVVHQLRPLHLCHFVLRLFDERTEQQSPKLANPSGIRRWSSSTLWKRLSFLVGITLTLLVGRVYVMGSQLPIFTRFDNPASAADTPERQLTYGYLIYLNCWLLLCPSLLCCDWTMGTVPLLQGFTDSRNITTLLTFLALGAMVAKTCFTRNLALSRTLIMCLGWMVLPFLPASNLFFPVGFVVAERILYMPSMGYCLLVAYGFEQLQRRGSLSWQRFSQAALAILLLTHALKTHQRNLDWRTEYSLFMSGVHVNQRNAKLYNNVGHALENEGKFEEALLYFQQAVRIQTDDIGAHINVGRTFNNLKRYAEAEQAYVQAKALFPQAKPGVSYHARIAPNHLNVFINLANLIAKNQTRLEEADHLYRQAISMRSDYVQAYINRGDILMKLNRTAQAQEVYEQALLYDNENADIYYNLGVVFLEQGKSQQAQVYFNKAIELYPEHEQALLNSAILLQELGGEEARRVSRSRLYKVLENDDQNEKVYFNLGMLAMDESSFDEAEQFFKRAIHLKADFRSALFNLALLLADTKRPLDAVPFLNQLIRHHPSHVKGLILLGDIYINHMKDLDEAEKCYRSILHYDPHNTQGLHNLCVVFVERKRLAKAAACLQYAQRLAPAEDYIGRHLQIVLARLQKINKLPESAPERKLAYEDYDPLEFKLPQDRPTHKSRKRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSTNPNPGI ------CCCCCCCCH	36.57	23607784
3	Phosphorylation	-----MSTNPNPGIH -----CCCCCCCCHH	54.09	23607784
12	Phosphorylation	PNPGIHQYAPSTLPR CCCCHHHCCCCCCCC	13.30	23607784
15	Phosphorylation	GIHQYAPSTLPRERE CHHHCCCCCCCCHHH	34.11	23607784
16	Phosphorylation	IHQYAPSTLPRERER HHHCCCCCCCCHHHH	39.46	23607784
609	N-linked_Glycosylation	LANLIAKNQTRLEEA HHHHHHHCCHHHHHH	39.16	-
645	N-linked_Glycosylation	GDILMKLNRTAQAQE HCHHHHCCCHHHHHH	33.47	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMTC3_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMTC3_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMTC3_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of TMTC3_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.