TMM98_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMM98_HUMAN
• UniProt AC: Q9Y2Y6
• Protein Name: Transmembrane protein 98
• Gene Name: TMEM98
• Organism: Homo sapiens (Human).
• Sequence Length: 226
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: METVVIVAIGVLATIFLASFAALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKGLPGPEGFLQEQSAI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
121	Phosphorylation	GSGAKMKTSASVSDI CCCCCCCCCCCHHHH	26.48	27251275
122	Phosphorylation	SGAKMKTSASVSDII CCCCCCCCCCHHHHH	17.02	27251275
124	Phosphorylation	AKMKTSASVSDIIVV CCCCCCCCHHHHHEE	23.17	26471730
126	Phosphorylation	MKTSASVSDIIVVAK CCCCCCHHHHHEEEC	22.16	27251275
136	Phosphorylation	IVVAKRISPRVDDVV HEEECCCCCCHHHHH	15.64	30631047
144	Ubiquitination	PRVDDVVKSMYPPLD CCHHHHHHHCCCCCC	29.38	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMM98_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMM98_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMM98_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TMM98_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• 615972: Nanophthalmos 4 (NNO4)
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.