TMG2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMG2_MOUSE
• UniProt AC: Q8R182
• Protein Name: Transmembrane gamma-carboxyglutamic acid protein 2
• Gene Name: Prrg2
• Organism: Mus musculus (Mouse).
• Sequence Length: 198
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Sequence: MRGRPSLLLVYMGLATCLDTSPHREQNQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYTYNGKGGRGRVDVAGLAVGLTSGILLIVLAGLGAFWYLHYRRRRLRGQESCLQETGLIIPLSPQTPQSPPLPPGLPTYEQALAASGVHDAPPPPYSSLRRPH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Gamma-carboxyglutamic_acid	LERECLEERCSWEEA HHHHHHHHHCCHHHH	46.14	-
193	Phosphorylation	APPPPYSSLRRPH-- CCCCCCHHCCCCC--	21.76	23140645

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMG2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMG2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMG2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NEDD4_MOUSE	Nedd4	physical	11042109

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.