TM9S1_HUMAN - dbPTM
TM9S1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TM9S1_HUMAN
UniProt AC O15321
Protein Name Transmembrane 9 superfamily member 1
Gene Name TM9SF1
Organism Homo sapiens (Human).
Sequence Length 606
Subcellular Localization Lysosome membrane
Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane
Multi-pass membrane protein .
Protein Description Plays an essential role in autophagy..
Protein Sequence MTVVGNPRSWSCQWLPILILLLGTGHGPGVEGVTHYKAGDPVILYVNKVGPYHNPQETYHYYQLPVCCPEKIRHKSLSLGEVLDGDRMAESLYEIRFRENVEKRILCHMQLSSAQVEQLRQAIEELYYFEFVVDDLPIRGFVGYMEESGFLPHSHKIGLWTHLDFHLEFHGDRIIFANVSVRDVKPHSLDGLRPDEFLGLTHTYSVRWSETSVERRSDRRRGDDGGFFPRTLEIHWLSIINSMVLVFLLVGFVAVILMRVLRNDLARYNLDEETTSAGSGDDFDQGDNGWKIIHTDVFRFPPYRGLLCAVLGVGAQFLALGTGIIVMALLGMFNVHRHGAINSAAILLYALTCCISGYVSSHFYRQIGGERWVWNIILTTSLFSVPFFLTWSVVNSVHWANGSTQALPATTILLLLTVWLLVGFPLTVIGGIFGKNNASPFDAPCRTKNIAREIPPQPWYKSTVIHMTVGGFLPFSAISVELYYIFATVWGREQYTLYGILFFVFAILLSVGACISIALTYFQLSGEDYRWWWRSVLSVGSTGLFIFLYSVFYYARRSNMSGAVQTVEFFGYSLLTGYVFFLMLGTISFFSSLKFIRYIYVNLKMD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
71UbiquitinationLPVCCPEKIRHKSLS
CCCCCCHHHCCCCCC		30.13-
75UbiquitinationCPEKIRHKSLSLGEV
CCHHHCCCCCCHHHC		43.15-
76PhosphorylationPEKIRHKSLSLGEVL
CHHHCCCCCCHHHCC		19.6421712546
78PhosphorylationKIRHKSLSLGEVLDG
HHCCCCCCHHHCCCH		41.2323312004
93PhosphorylationDRMAESLYEIRFREN
HHHHHHHHHHHCHHC		20.7024505115
154PhosphorylationESGFLPHSHKIGLWT
HCCCCCCCCEEEEEE		25.24-
178N-linked_GlycosylationGDRIIFANVSVRDVK
CCEEEEEEEEECCCC		18.82UniProtKB CARBOHYD
188PhosphorylationVRDVKPHSLDGLRPD
ECCCCCCCCCCCCCC		36.36-
201PhosphorylationPDEFLGLTHTYSVRW
CCHHCCCEEEEEEEC		15.4626074081
203PhosphorylationEFLGLTHTYSVRWSE
HHCCCEEEEEEECCC		16.5626074081
204PhosphorylationFLGLTHTYSVRWSET
HCCCEEEEEEECCCC		9.5126074081
205PhosphorylationLGLTHTYSVRWSETS
CCCEEEEEEECCCCE		13.3226074081
209PhosphorylationHTYSVRWSETSVERR
EEEEEECCCCEEECC		22.0426074081
211PhosphorylationYSVRWSETSVERRSD
EEEECCCCEEECCHH		32.3426074081
212PhosphorylationSVRWSETSVERRSDR
EEECCCCEEECCHHC		20.2326074081
268PhosphorylationLRNDLARYNLDEETT
HHHHHHHCCCCCCCC		17.9220873877
274PhosphorylationRYNLDEETTSAGSGD
HCCCCCCCCCCCCCC		24.8120873877
275PhosphorylationYNLDEETTSAGSGDD
CCCCCCCCCCCCCCC		21.6227251275
276PhosphorylationNLDEETTSAGSGDDF
CCCCCCCCCCCCCCC		37.7426471730
279PhosphorylationEETTSAGSGDDFDQG
CCCCCCCCCCCCCCC		38.4727251275
291UbiquitinationDQGDNGWKIIHTDVF
CCCCCCEEEEEEECE		32.932190698
401N-linked_GlycosylationVNSVHWANGSTQALP
HCCHHHCCCCCCCCC		39.49UniProtKB CARBOHYD
500UbiquitinationEQYTLYGILFFVFAI
HHHHHHHHHHHHHHH		1.5921906983
535PhosphorylationDYRWWWRSVLSVGST
CHHHHHHHHHCCCHH		17.4325072903
538PhosphorylationWWWRSVLSVGSTGLF
HHHHHHHCCCHHHHH		23.4425072903
541PhosphorylationRSVLSVGSTGLFIFL
HHHHCCCHHHHHHHH		19.6925072903
542PhosphorylationSVLSVGSTGLFIFLY
HHHCCCHHHHHHHHH		31.7925072903
549PhosphorylationTGLFIFLYSVFYYAR
HHHHHHHHHHHHHHH		7.6425072903
550PhosphorylationGLFIFLYSVFYYARR
HHHHHHHHHHHHHHH		14.1125072903
553PhosphorylationIFLYSVFYYARRSNM
HHHHHHHHHHHHCCC		8.2825072903
554PhosphorylationFLYSVFYYARRSNMS
HHHHHHHHHHHCCCC		5.1225072903
558PhosphorylationVFYYARRSNMSGAVQ
HHHHHHHCCCCCCCC		31.1925072903
559N-linked_GlycosylationFYYARRSNMSGAVQT
HHHHHHCCCCCCCCC		27.16UniProtKB CARBOHYD
561PhosphorylationYARRSNMSGAVQTVE
HHHHCCCCCCCCCCH		28.0525072903
566PhosphorylationNMSGAVQTVEFFGYS
CCCCCCCCCHHHHHH		18.5325072903
572PhosphorylationQTVEFFGYSLLTGYV
CCCHHHHHHHHHHHH		7.3225072903
573PhosphorylationTVEFFGYSLLTGYVF
CCHHHHHHHHHHHHH		19.7925072903
576PhosphorylationFFGYSLLTGYVFFLM
HHHHHHHHHHHHHHH		31.5925072903
578PhosphorylationGYSLLTGYVFFLMLG
HHHHHHHHHHHHHHH		6.7225072903
586PhosphorylationVFFLMLGTISFFSSL
HHHHHHHHHHHHHHC		14.9725072903
588PhosphorylationFLMLGTISFFSSLKF
HHHHHHHHHHHHCHH		21.7825072903
591PhosphorylationLGTISFFSSLKFIRY
HHHHHHHHHCHHHHH		32.5225072903
592PhosphorylationGTISFFSSLKFIRYI
HHHHHHHHCHHHHHH		30.3525072903
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TM9S1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TM9S1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TM9S1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TM9S1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TM9S1_HUMAN

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Related Literatures of Post-Translational Modification

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