TM6S1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM6S1_HUMAN
• UniProt AC: Q9BZW5
• Protein Name: Transmembrane 6 superfamily member 1
• Gene Name: TM6SF1
• Organism: Homo sapiens (Human).
• Sequence Length: 370
• Subcellular Localization: Lysosome membrane ; Multi-pass membrane protein .
• Protein Description: May function as sterol isomerase..
• Protein Sequence: MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFFIKTKAEEKVE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
356	Ubiquitination	LAYRCIYKPEFFIKT HHHHHHHCCHHEEEE	20.40	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM6S1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM6S1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM6S1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM6S1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.