TM35B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM35B_HUMAN
• UniProt AC: Q8NCS4
• Protein Name: Transmembrane protein 35B
• Gene Name: TMEM35B {ECO:0000312|HGNC:HGNC:40021}
• Organism: Homo sapiens (Human).
• Sequence Length: 154
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MALLLSVLRVLLGGFFALVGLAKLSEEISAPVSERMNALFVQFAEVFPLKVFGYQPDPLNYQIAVGFLELLAGLLLVMGPPMLQEISNLFLILLMMGAIFTLAALKESLSTCIPAIVCLGFLLLLNVGQLLAQTKKVVRPTRKKTLSTFKESWK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MALLLSVLRVLLG --CHHHHHHHHHHHH		20068231
144	Ubiquitination	VVRPTRKKTLSTFKE CCCCCCCCCHHHHHH		33845483
145	Phosphorylation	VRPTRKKTLSTFKES CCCCCCCCHHHHHHH		23312004
147	Phosphorylation	PTRKKTLSTFKESWK CCCCCCHHHHHHHCC		28348404
148	Phosphorylation	TRKKTLSTFKESWK- CCCCCHHHHHHHCC-		29853039
150	Ubiquitination	KKTLSTFKESWK--- CCCHHHHHHHCC---		29967540
152	Phosphorylation	TLSTFKESWK----- CHHHHHHHCC-----		28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM35B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM35B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM35B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM35B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.