TM263_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM263_HUMAN
• UniProt AC: Q8WUH6
• Protein Name: Transmembrane protein 263
• Gene Name: TMEM263
• Organism: Homo sapiens (Human).
• Sequence Length: 116
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MNQTDKNQQEIPSYLNDEPPEGSMKDHPQQQPGMLSRVTGGIFSVTKGAVGATIGGVAWIGGKSLEVTKTAVTTVPSMGIGLVKGGVSAVAGGVTAVGSAVVNKVPLTGKKKDKSD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-linked_Glycosylation	------MNQTDKNQQ ------CCCCCCCHH		UniProtKB CARBOHYD
14	Phosphorylation	NQQEIPSYLNDEPPE CHHCCCHHHCCCCCC		28555341
23	Phosphorylation	NDEPPEGSMKDHPQQ CCCCCCCCCCCCCCC		25159151
25	Ubiquitination	EPPEGSMKDHPQQQP CCCCCCCCCCCCCCC		-
39	Phosphorylation	PGMLSRVTGGIFSVT CCHHHHHHCCEEEEC		29396449
39	O-linked_Glycosylation	PGMLSRVTGGIFSVT CCHHHHHHCCEEEEC		55821213
44	Phosphorylation	RVTGGIFSVTKGAVG HHHCCEEEECCCCCC		25159151
46	Phosphorylation	TGGIFSVTKGAVGAT HCCEEEECCCCCCCE		29396449
46	O-linked_Glycosylation	TGGIFSVTKGAVGAT HCCEEEECCCCCCCE		55821219
47	Ubiquitination	GGIFSVTKGAVGATI CCEEEECCCCCCCEE		-
53	O-linked_Glycosylation	TKGAVGATIGGVAWI CCCCCCCEEECEEEE		OGP
63	Acetylation	GVAWIGGKSLEVTKT CEEEECCEEEEEEEE		26051181
64	O-linked_Glycosylation	VAWIGGKSLEVTKTA EEEECCEEEEEEEEE		28657654
64	Phosphorylation	VAWIGGKSLEVTKTA EEEECCEEEEEEEEE		24719451
69	Ubiquitination	GKSLEVTKTAVTTVP CEEEEEEEEEEECCC		29967540
70	Phosphorylation	KSLEVTKTAVTTVPS EEEEEEEEEEECCCC		20860994
70	O-linked_Glycosylation	KSLEVTKTAVTTVPS EEEEEEEEEEECCCC		28510447
73	Phosphorylation	EVTKTAVTTVPSMGI EEEEEEEECCCCCCC		20860994
73	O-linked_Glycosylation	EVTKTAVTTVPSMGI EEEEEEEECCCCCCC		28510447
74	Phosphorylation	VTKTAVTTVPSMGIG EEEEEEECCCCCCCC		28857561
74	O-linked_Glycosylation	VTKTAVTTVPSMGIG EEEEEEECCCCCCCC		28510447
77	Phosphorylation	TAVTTVPSMGIGLVK EEEECCCCCCCCEEC		29116813
77	O-linked_Glycosylation	TAVTTVPSMGIGLVK EEEECCCCCCCCEEC		28510447
88	Phosphorylation	GLVKGGVSAVAGGVT CEECCCCEEEECCEE		28857561
88	O-linked_Glycosylation	GLVKGGVSAVAGGVT CEECCCCEEEECCEE		OGP
95	O-linked_Glycosylation	SAVAGGVTAVGSAVV EEEECCEEEECEEEE		OGP
99	O-linked_Glycosylation	GGVTAVGSAVVNKVP CCEEEECEEEECCCC		OGP
99	Phosphorylation	GGVTAVGSAVVNKVP CCEEEECEEEECCCC		21712546
104	Ubiquitination	VGSAVVNKVPLTGKK ECEEEECCCCCCCCC		29967540
108	Phosphorylation	VVNKVPLTGKKKDKS EECCCCCCCCCCCCC		21712546
110	Acetylation	NKVPLTGKKKDKSD- CCCCCCCCCCCCCC-		25953088
110	Ubiquitination	NKVPLTGKKKDKSD- CCCCCCCCCCCCCC-		-
111	Acetylation	KVPLTGKKKDKSD-- CCCCCCCCCCCCC--		30587255

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM263_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM263_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM263_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM263_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.