TM242_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM242_HUMAN
• UniProt AC: Q9NWH2
• Protein Name: Transmembrane protein 242
• Gene Name: TMEM242
• Organism: Homo sapiens (Human).
• Sequence Length: 141
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: METAGAATGQPASGLEAPGSTNDRLFLVKGGIFLGTVAAAGMLAGFITTLSLAKKKSPEWFNKGSMATAALPESGSSLALRALGWGSLYAWCGVGVISFAVWKALGVHSMNDFRSKMQSIFPTIPKNSESAVEWEETLKSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------METAGAAT -------CCCCCCCC	10.48	22814378
8	Phosphorylation	METAGAATGQPASGL CCCCCCCCCCCCCCC	35.50	24719451
21	Phosphorylation	GLEAPGSTNDRLFLV CCCCCCCCCCCEEEE	47.24	24719451
48	Phosphorylation	GMLAGFITTLSLAKK HHHHHHHHHHHHHHH	21.30	-
49	Phosphorylation	MLAGFITTLSLAKKK HHHHHHHHHHHHHHC	14.99	-
51	Phosphorylation	AGFITTLSLAKKKSP HHHHHHHHHHHHCCH	24.96	-
89	Phosphorylation	ALGWGSLYAWCGVGV HHCCHHHHHHHHHHH	10.35	-
116	Ubiquitination	SMNDFRSKMQSIFPT CHHHHHHHHHHHCCC	36.38	27667366
139	Ubiquitination	VEWEETLKSK----- CCHHHHHHCC-----	64.71	32015554

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM242_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM242_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM242_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM242_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.