| UniProt ID | TM222_HUMAN | |
|---|---|---|
| UniProt AC | Q9H0R3 | |
| Protein Name | Transmembrane protein 222 | |
| Gene Name | TMEM222 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 208 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MAEAEGSSLLLLPPPPPPPRMAEVEAPTAAETDMKQYQGSGGVAMDVERSRFPYCVVWTPIPVLTWFFPIIGHMGICTSTGVIRDFAGPYFVSEDNMAFGKPAKYWKLDPAQVYASGPNAWDTAVHDASEEYKHRMHNLCCDNCHSHVALALNLMRYNNSTNWNMVTLCFFCLLYGKYVSVGAFVKTWLPFILLLGIILTVSLVFNLR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 (in isoform 2) | Ubiquitination | - | 25.38 | 21906983 | |
| 7 | Phosphorylation | -MAEAEGSSLLLLPP -CCCCCCCCEEECCC | 14.87 | - | |
| 8 | Phosphorylation | MAEAEGSSLLLLPPP CCCCCCCCEEECCCC | 33.61 | - | |
| 35 | Ubiquitination | TAAETDMKQYQGSGG CCCCCHHHHHCCCCC | 48.98 | 21906983 | |
| 40 | Phosphorylation | DMKQYQGSGGVAMDV HHHHHCCCCCEECCC | 19.49 | 26471730 | |
| 68 (in isoform 2) | Ubiquitination | - | 2.99 | 21906983 | |
| 74 (in isoform 2) | Ubiquitination | - | 3.05 | 21906983 | |
| 100 (in isoform 2) | Ubiquitination | - | 26.04 | 21906983 | |
| 101 | Ubiquitination | EDNMAFGKPAKYWKL CCCCCCCCCCCCEEC | 35.04 | 21906983 | |
| 101 (in isoform 1) | Ubiquitination | - | 35.04 | 21906983 | |
| 104 | Ubiquitination | MAFGKPAKYWKLDPA CCCCCCCCCEECCHH | 61.24 | - | |
| 107 | Ubiquitination | GKPAKYWKLDPAQVY CCCCCCEECCHHHHH | 39.66 | 21906983 | |
| 107 (in isoform 1) | Ubiquitination | - | 39.66 | 21906983 | |
| 133 | Ubiquitination | HDASEEYKHRMHNLC HHHCHHHHHHHHHHC | 28.19 | 21963094 | |
| 133 (in isoform 1) | Ubiquitination | - | 28.19 | 21906983 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TM222_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TM222_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TM222_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TM222_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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