TM203_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM203_HUMAN
• UniProt AC: Q969S6
• Protein Name: Transmembrane protein 203
• Gene Name: TMEM203
• Organism: Homo sapiens (Human).
• Sequence Length: 136
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Description: Involved in the regulation of cellular calcium homeotasis. [PubMed: 25996873 Required for spermatogenesis]
• Protein Sequence: MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLVPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLAEQTRELWFGLITSPLFILLQLLMIRACRVN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
68	Phosphorylation	TYFTTIVSVRLFQDG HHHHHHEEEEECCCC	9.54	24719451
92	Phosphorylation	FWVLTVLSLKFVFEM HHHHHHHHHHHHHHH	25.77	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM203_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM203_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM203_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM203_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.