TM201_MOUSE - dbPTM
TM201_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TM201_MOUSE
UniProt AC A2A8U2
Protein Name Transmembrane protein 201
Gene Name Tmem201
Organism Mus musculus (Mouse).
Sequence Length 664
Subcellular Localization Isoform 2: Nucleus inner membrane
Multi-pass membrane protein . The C-terminal of isoform 2 is located on the nucleoplasmic side. During interphase, isoform 2 is distributed in the inner nuclear membrane and during mitosis, it is found in the ER bu
Protein Description Involved in nuclear movement during fibroblast polarization and migration. [PubMed: 22349700 May recruit Ran GTPase to the nuclear periphery (By similarity; Isoform 2: May define a distinct membrane domain in the vicinity of the mitotic spindle. Involved in the organization of the nuclear envelope implicating EMD, SUN1 and A-type lamina.; Isoform 3: Proposed to be involved in actin-dependent nuclear movement; via SUN2 associates with transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow.]
Protein Sequence MEGVSALLASCPTAGLAGGLGVTACAAAGVVLYRIARRVKPTHTMVNCWFCNHDTLVPYGNRNCWDCPHCEQYNGFQENGDYNKPIPAQYMEHLNHVVSSVPSPRDPAQPQQWVSSQVLLCRRCSHHQTTKIKQLAAFTPREEGRYDEEIEVYRHHLEQMYKLCRPCQAAVEYYIKHQNRQLRALLLSHQFRRREADQAHGQSFSSSAVKAPFQVILLRALAFLACAFLLFTTLYGPSEPFTPGAALPPALPPGGNSSAASDNTTSQAEGWQQLLGLLPEHATEKLHEAWAFGQSHQTSIVAVGLLTCLLAMLLAGRIRLRRIDAFSTCLWALLLGLHLAEHYLQAASPGWLDTLKFSTTSLCCLVGFTAAVATRKSTGPRRFRPRRYFSGDSASLFPSSPSLAVPYPSVTSSPASLFIPTPPGFLPLTKQQLFRSPRRVSPSSLPGRLSRALSLGTIPPLTRTDSGYLFSGSRPPSRVSPAGEVSLSDYFSLLSSSFPASPLPSPAPSVASSVASSSGSLRHRRPLISPARLNLKGQKLLLFSSPGEAPNTPSSSEEFSPPNGSLFIESPQLPQRNHTRDTKHTMEMRSMLARDSARSSHSIKKEDESSQSSTCVVDTTTKGCSEETTPWKARVSPSLVRGLLAVSLAVNALFTSAYLYQSLR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
1Acetylation-------MEGVSALL
-------CCHHHHHH		10.24-
133MalonylationHHQTTKIKQLAAFTP
CCCCCCHHHHHCCCC		40.5926320211
203PhosphorylationADQAHGQSFSSSAVK
HHHHCCCCCCHHHCH		31.5225159016
205PhosphorylationQAHGQSFSSSAVKAP
HHCCCCCCHHHCHHH		28.7328066266
206PhosphorylationAHGQSFSSSAVKAPF
HCCCCCCHHHCHHHH		21.9528066266
207PhosphorylationHGQSFSSSAVKAPFQ
CCCCCCHHHCHHHHH		35.5628066266
388PhosphorylationRRFRPRRYFSGDSAS
CCCCCCCCCCCCCCC		11.9023984901
390PhosphorylationFRPRRYFSGDSASLF
CCCCCCCCCCCCCCC		32.5323984901
393PhosphorylationRRYFSGDSASLFPSS
CCCCCCCCCCCCCCC		24.2323984901
395PhosphorylationYFSGDSASLFPSSPS
CCCCCCCCCCCCCCC		34.2023984901
399PhosphorylationDSASLFPSSPSLAVP
CCCCCCCCCCCCCCC		47.7723984901
400PhosphorylationSASLFPSSPSLAVPY
CCCCCCCCCCCCCCC		20.8123984901
402PhosphorylationSLFPSSPSLAVPYPS
CCCCCCCCCCCCCCC		30.7923984901
407PhosphorylationSPSLAVPYPSVTSSP
CCCCCCCCCCCCCCC		11.0923984901
409PhosphorylationSLAVPYPSVTSSPAS
CCCCCCCCCCCCCCC		31.9823984901
411PhosphorylationAVPYPSVTSSPASLF
CCCCCCCCCCCCCCC		28.0223984901
412PhosphorylationVPYPSVTSSPASLFI
CCCCCCCCCCCCCCC		31.9723984901
413PhosphorylationPYPSVTSSPASLFIP
CCCCCCCCCCCCCCC		18.3423984901
416PhosphorylationSVTSSPASLFIPTPP
CCCCCCCCCCCCCCC		27.4823984901
421PhosphorylationPASLFIPTPPGFLPL
CCCCCCCCCCCCCCC		36.9823984901
436PhosphorylationTKQQLFRSPRRVSPS
CHHHHHCCCCCCCCC		18.5429514104
441PhosphorylationFRSPRRVSPSSLPGR
HCCCCCCCCCCCCCH		19.7726824392
443PhosphorylationSPRRVSPSSLPGRLS
CCCCCCCCCCCCHHH		36.6828833060
444PhosphorylationPRRVSPSSLPGRLSR
CCCCCCCCCCCHHHH		41.8028833060
450PhosphorylationSSLPGRLSRALSLGT
CCCCCHHHHHHHCCC		17.7229514104
454PhosphorylationGRLSRALSLGTIPPL
CHHHHHHHCCCCCCC		24.6226824392
457PhosphorylationSRALSLGTIPPLTRT
HHHHHCCCCCCCCCC		35.2923984901
464PhosphorylationTIPPLTRTDSGYLFS
CCCCCCCCCCCCEEC		29.3126643407
466PhosphorylationPPLTRTDSGYLFSGS
CCCCCCCCCCEECCC		28.8225266776
468PhosphorylationLTRTDSGYLFSGSRP
CCCCCCCCEECCCCC		14.4429472430
471PhosphorylationTDSGYLFSGSRPPSR
CCCCCEECCCCCCCC		33.0128285833
477PhosphorylationFSGSRPPSRVSPAGE
ECCCCCCCCCCCCCE		48.2524899341
480PhosphorylationSRPPSRVSPAGEVSL
CCCCCCCCCCCEECH		14.12-
517PhosphorylationVASSVASSSGSLRHR
HHHHHHHCCCCCCCC		29.0521183079
518PhosphorylationASSVASSSGSLRHRR
HHHHHHCCCCCCCCC		29.8821183079
529PhosphorylationRHRRPLISPARLNLK
CCCCCCCCHHHCCCC		21.86-
609PhosphorylationSIKKEDESSQSSTCV
CCCCCCCCCCCCEEE		46.1023375375
610PhosphorylationIKKEDESSQSSTCVV
CCCCCCCCCCCEEEE		31.8423375375
612PhosphorylationKEDESSQSSTCVVDT
CCCCCCCCCEEEEEC		29.5723375375
613PhosphorylationEDESSQSSTCVVDTT
CCCCCCCCEEEEECC		20.4223375375
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TM201_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TM201_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TM201_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TM201_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TM201_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory