TM14C_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM14C_MOUSE
• UniProt AC: Q9CQN6
• Protein Name: Transmembrane protein 14C
• Gene Name: Tmem14c
• Organism: Mus musculus (Mouse).
• Sequence Length: 114
• Subcellular Localization: Mitochondrion membrane; Multi-pass membrane protein.
• Protein Description: Required for normal heme biosynthesis..
• Protein Sequence: MQKDSGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	Phosphorylation	NVWVFLATSGTLAGI CEEEEEEECCCHHHH	29.81	-
70	Phosphorylation	VWVFLATSGTLAGIM EEEEEEECCCHHHHH	24.95	-
110	Phosphorylation	KVGISLLSSPHP--- HHHHHHHCCCCC---	47.30	26643407
111	Phosphorylation	VGISLLSSPHP---- HHHHHHCCCCC----	27.48	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM14C_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM14C_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM14C_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TM14C_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.