TM101_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM101_HUMAN
• UniProt AC: Q96IK0
• Protein Name: Transmembrane protein 101
• Gene Name: TMEM101
• Organism: Homo sapiens (Human).
• Sequence Length: 257
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: May activate NF-kappa-B signaling pathways..
• Protein Sequence: MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGILALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
110	Phosphorylation	DWLKVRMYSRTVAII CHHHHHCCCCEEEEE	5.62	24043423
111	Phosphorylation	WLKVRMYSRTVAIIG HHHHHCCCCEEEEEH	16.48	24043423
113	Phosphorylation	KVRMYSRTVAIIGGF HHHCCCCEEEEEHHH	14.35	24043423
125	Phosphorylation	GGFLVLASGAGELYR HHHHHHCCCCHHHHH	25.64	24043423
131	Phosphorylation	ASGAGELYRRKPRSR CCCCHHHHHCCCCCC	12.22	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM101_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM101_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM101_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TM101_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.