TLC2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TLC2_ARATH
• UniProt AC: P92935
• Protein Name: ADP,ATP carrier protein 2, chloroplastic
• Gene Name: AATP2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 618
• Subcellular Localization: Plastid, chloroplast membrane ; Multi-pass membrane protein .
• Protein Sequence: MEGLIQTRGILSLPAKPIGVRRLLQPSHGLKQRLFTTNLPALSLSSNGHKKFQAFQQIPLGISVSHKERSRGFICKAEAAAAGGGNVFDEGDTAAMAVSPKIFGVEVTTLKKIVPLGLMFFCILFNYTILRDTKDVLVVTAKGSSAEIIPFLKTWVNLPMAIGFMLLYTKLSNVLSKKALFYTVIVPFIVYFGAFGFVMYPLSNLIHPEALADKLLATLGPRFMGPLAIMRIWSFCLFYVMAELWGSVVVSVLFWGFANQITTVDEAKKFYPLFGLGANVALIFSGRTVKYFSNMRKNLGPGVDGWAVSLKAMMSIVVGMGLAICFLYWWVNRYVPLPTRSKKKKVKPQMGTMESLKFLVSSPYIRDLATLVVAYGISINLVEVTWKSKLKAQFPSPNEYSAFMGDFSTCTGIATFTMMLLSQYVFKKYGWGVAAKITPTVLLLTGVAFFSLILFGGPFAPLVAKLGMTPLLAAVYVGALQNIFSKSAKYSLFDPCKEMAYIPLDEDTKVKGKAAIDVVCNPLGKSGGALIQQFMILTFGSLANSTPYLGVILLGIVTAWLAAAKSLEGQFNTLMSEEELEREMERASSVKIPVVSQEDAPSGETTSQLSEKSTPTGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MEGLIQTRGILSLP -CCCCCCCCCCCCCC	24.70	24894044
77	Acetylation	SRGFICKAEAAAAGG HCCEEEEHHHHHCCC	13.78	22223895
339	Phosphorylation	NRYVPLPTRSKKKKV HHCCCCCCCCCCCCC	56.08	24894044
341	Phosphorylation	YVPLPTRSKKKKVKP CCCCCCCCCCCCCCC	51.83	24894044
588	Phosphorylation	EREMERASSVKIPVV HHHHHHHHCCCCCEE	41.72	19376835
589	Phosphorylation	REMERASSVKIPVVS HHHHHHHCCCCCEEC	26.84	19376835
596	Phosphorylation	SVKIPVVSQEDAPSG CCCCCEECCCCCCCC	28.25	19376835
602	Phosphorylation	VSQEDAPSGETTSQL ECCCCCCCCCCCHHH	51.48	19376835
605	Phosphorylation	EDAPSGETTSQLSEK CCCCCCCCCHHHCCC	34.96	19376835
606	Phosphorylation	DAPSGETTSQLSEKS CCCCCCCCHHHCCCC	15.35	19376835
607	Phosphorylation	APSGETTSQLSEKST CCCCCCCHHHCCCCC	36.22	19376835
610	Phosphorylation	GETTSQLSEKSTPTG CCCCHHHCCCCCCCC	35.03	19376835

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TLC2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TLC2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TLC2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CNIH1_ARATH	AT3G12180	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.