TIS11_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TIS11_DROME
• UniProt AC: P47980
• Protein Name: Protein TIS11
• Gene Name: Tis11
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 436
• Subcellular Localization: Nucleus .
• Protein Sequence: MSADILQKSREQDDSHYFERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPISPVHTPPPYDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNLGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
122	Phosphorylation	RKLERTQSEPLPPQQ HHHHHHCCCCCCCCC		21082442
184	Phosphorylation	EYCRTFHSVGFCPYG CCCCCCCCCCCCCCC		22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TIS11_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TIS11_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TIS11_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EYA_DROME	eya	physical	22553461

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.