TIM22_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TIM22_DROME
• UniProt AC: Q8IN78
• Protein Name: Mitochondrial import inner membrane translocase subunit Tim22
• Gene Name: Tim22
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 195
• Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein.
• Protein Description: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity)..
• Protein Sequence: MSVLPNAGNNESSVTAPKMFGDPDLDRMAMEYVGNMQRYRENIIIPKSNGPVKIKTNEEKFIETAVESCGFKCTMACVMGYGLGAALGLFSASVNPNMADPFANEKKQTAREVFREMRSTTHSYAKNFALIGCVFSAVECTIESHRGVTDWKNGTYAGGITGGLIGLRAGVKAGIIGGLGFAAFSTAIDYYMYSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of TIM22_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TIM22_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TIM22_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TIM22_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of TIM22_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.