| UniProt ID | TICN1_HUMAN | |
|---|---|---|
| UniProt AC | Q08629 | |
| Protein Name | Testican-1 | |
| Gene Name | SPOCK1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 439 | |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. | |
| Protein Description | May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.. | |
| Protein Sequence | MPAIAVLAAAAAAWCFLQVESRHLDALAGGAGPNHGNFLDNDQWLSTVSQYDRDKYWNRFRDDDYFRNWNPNKPFDQALDPSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAERSACTDKELRNLASRLKDWFGALHEDANRVIKPTSSNTAQGRFDTSILPICKDSLGWMFNKLDMNYDLLLDPSEINAIYLDKYEPCIKPLFNSCDSFKDGKLSNNEWCYCFQKPGGLPCQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGSRKQGAVSCEEEQETSGDFGSGGSVVLLDDLEYERELGPKDKEGKLRVHTRAVTEDDEDEDDDKEDEVGYIW | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 21 | Phosphorylation | WCFLQVESRHLDALA HHHHHHHHHHHHHHC | 26.58 | 25332170 | |
| 65 | Phosphorylation | NRFRDDDYFRNWNPN HHHCCCCHHHCCCCC | 16.07 | - | |
| 118 | Acetylation | KHLLPRQKKGNVAQK HHHCCCCCCCCCCCC | 65.02 | 87845 | |
| 119 | Acetylation | HLLPRQKKGNVAQKH HHCCCCCCCCCCCCC | 47.59 | 133839 | |
| 131 | Phosphorylation | QKHWVGPSNLVKCKP CCCCCCHHHCCEEEE | 36.55 | - | |
| 131 | O-linked_Glycosylation | QKHWVGPSNLVKCKP CCCCCCHHHCCEEEE | 36.55 | 68702357 | |
| 144 | Phosphorylation | KPCPVAQSAMVCGSD EECCCCCEEEEECCC | 14.48 | - | |
| 150 | Phosphorylation | QSAMVCGSDGHSYTS CEEEEECCCCCCCCC | 34.98 | - | |
| 226 | Ubiquitination | EDANRVIKPTSSNTA HCCCCCCCCCCCCCC | 39.11 | 29967540 | |
| 228 | O-linked_Glycosylation | ANRVIKPTSSNTAQG CCCCCCCCCCCCCCC | 39.52 | 55834829 | |
| 248 | Phosphorylation | ILPICKDSLGWMFNK HHHHHHHHHHHHHHH | 17.80 | - | |
| 346 | Phosphorylation | EEGYYKATQCHGSTG CCCCEEEEEECCCCC | 27.81 | - | |
| 351 | Phosphorylation | KATQCHGSTGQCWCV EEEEECCCCCCEEEE | 13.00 | - | |
| 352 | Phosphorylation | ATQCHGSTGQCWCVD EEEECCCCCCEEEEC | 35.54 | - | |
| 383 | O-linked_Glycosylation | CEEEQETSGDFGSGG CCCCHHCCCCCCCCC | 35.30 | - | |
| 388 | O-linked_Glycosylation | ETSGDFGSGGSVVLL HCCCCCCCCCEEEEE | 39.72 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TICN1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TICN1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TICN1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TICN1_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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