TI214_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TI214_ARATH
• UniProt AC: P56785
• Protein Name: Protein TIC 214 {ECO:0000303|PubMed:23372012}
• Gene Name: TIC214 {ECO:0000303|PubMed:23372012}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1786
• Subcellular Localization: Plastid, chloroplast inner membrane ; Multi-pass membrane protein .
• Protein Description: Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope..
• Protein Sequence: MMVFQSFILGNLVSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMDEGEEGTEKKVSATTGFIAGQLMMFISIYYAPLHLALGRPHTITVLALPYLLFHFFWNNHKHFFDYGSTTRNEMRNLRIQCVFLNNLIFQLFNHFILPSSMLARLVNIYMFRCNNKMLFVTSSFVGWLIGHILFMKWVGLVLVWIQQNNSIRSNVVIRSNKYKFLVSELRNSMARIFSILLFITCVYYLGRIPSPIFTKKLKGTSETGGTKQDQEVSTEEAPFPSLFSEEGEDLDKIDEMEEIRVNGKDKINKDDEFHVRTYYNYKTVSENLYGNKENSNLEFFKIKKKEDHFLWFEKPFVTLVFDYKRWNRPNRYIKNDKIENIVRNEMSQYFFYTCQSDGKERISFTYPPNLSTFFEMIQKRIPSFTKEKKTFDQVSTYWSLIHEEKRENLKKEFLNRIEALDKEWSVENILEKTTRFCYNEAKKEYLPKIYDPFLHGISRGRIKKLPPFQIITETYRKNNLGGSWINKIHGLLLKINYKKFEQTIEKFNRKSLSIEKKLSFFSEPQQEEKINSEEEIKTFKFLFDIVRTDSNDQTLIKNFMDFPEINKKVPRWSYKLISELEELEGENEENVPMEPGIRSRKAKRVVVFTDKEPHGEIYTNLKDNQNSDQNDEMALIRYSQQSDFRREIIKGSMRSQRRKTVIWEFFQAKVHSPLFFDRIDKLFFFSFDIWGLKKKIIKNFIWKKKIDKKEEEQSKREETRRIEIAETWDSFLFAQIIRGSLLVTQSILRKYIILPLLIIIKNSVRMLLFQFPEWSQDLKDWKREMHVKCTYNGVQLSETEFPRNWLTDGIQIKILFPFYLKPWHKSKFQASQKARLKKTKDKGEKNDFCFLTVWGMETELPFGSAQRKPSFFEPISKELKKRIKKLKKKSFVVLKIFKERAPIFLKVAKETKNWILKNFIFIKGISKRNLIPLFGPREIYELNEPKKDSIISNQMIHELSVQNKSLEWTNSSLSEKKIKNLIDRKKTIRNQIEEISKEKQNLTNSCTKLRYDSKIIESSKKIWQTFKRKNTRLIRKSIFFFKFCIEQMSIAIFLGIINIPRITTQLFFESTKKILDKYIYKNEENGEKKKNTLYFISTIKNLISNKKKMSYDLCSLSQAYVFYKLSQIKVSNFCKLKAVLEYNICITSFFVKNKIKVFFQEHGIFHYELKNKTFLNSEVNQWKNWLRSQYQYNLPQISWARLVTQNWKNKINKDSLVLNPSLTKEDSYEKKKFDNYKKQKFFEADSLLNPKHNVKKDSIYNLFCYKSIHSTEKNFDMSIGIALDNCLVSSFLEKYNIRGMGEIRHRKYLDWRILNFWFTKKVTIEPWVDTKSKKKYINTKVQNYQKIDKITQTDLANKKRNFFDWMGMNEEILNQRITNFEFFFFPEFFLFSSTYKMKPWVIPIKLLLLNFNENINVNKKIIRKKKGFIPSNEKESLRFYNLNKEEKESAGQVELESDKETKRNPEAARLNQEKNIEENFAESTIKKRKNKKQYKSNTEAELDLFLTRYSRFQLRWNCFFNQKILNNVKVYCLLVRLNNPNEIAVSSIERGEMSLDILMIEKNFTFAKLMKKGILIIEPVRLSVQNDGQLIIYRTIGISLVHKNKHKISKRYKKKSYINKKFFEKSITKYQNKTVNKKKNNYDFFVPEKILSPKRRREFRILICFNLKKKNARDTNSRFDKNIQNLTTVLHKKKDLDLDKDKNNLINLKSFLWPNFKLEDLACMNRYWFNTTNGNHFSMIRIRMYTRFPIP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
245	Phosphorylation	YYLGRIPSPIFTKKL HHHCCCCCCCCCCCC		19880383
249	Phosphorylation	RIPSPIFTKKLKGTS CCCCCCCCCCCCCCC		19880383
554	Phosphorylation	LSIEKKLSFFSEPQQ CCHHHHHHCCCCHHH		19376835
557	Phosphorylation	EKKLSFFSEPQQEEK HHHHHCCCCHHHHHC		19376835
905	Phosphorylation	GSAQRKPSFFEPISK CCCCCCCCCCHHCCH		19880383
1004	Phosphorylation	QNKSLEWTNSSLSEK CCCCCCCCCCCCCHH		19880383
1006	Phosphorylation	KSLEWTNSSLSEKKI CCCCCCCCCCCHHHH		19880383
1007	Phosphorylation	SLEWTNSSLSEKKIK CCCCCCCCCCHHHHH		19880383
1492	Phosphorylation	AGQVELESDKETKRN CCCCCCCCCHHCCCC		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TI214_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TI214_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TI214_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of TI214_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.