THO5B_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: THO5B_ARATH
• UniProt AC: F4K4J0
• Protein Name: THO complex subunit 5B
• Gene Name: THO5B
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 819
• Subcellular Localization: Nucleus .
• Protein Description: Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export..
• Protein Sequence: MEDGEIEEGMVTADEFPTPEVTTIETIQPPREPGKSPLELLRESKTSVEEIVAKMLSMKKQGNHKSEIRELLTQMFLNFVNLRQANRAILTEEDKVKAETERAKAPVDFTTLQLHNLMYEKSHYVKAIKACRDFKSKYPDIDLVPEQDFFRHAPEAIKDQSLSSDSSHVLMPKRLNFELHQRKELCKHRARLEQQKKSLLETIAERKKFLSSLPLHLKSLKKASLPVQNHLGIQHTKKLKQHNLAELLPPPLYVLYSQLLAQKEAFEESIELEVVGSLKDAQAYARQQSRKDSGMSSNTESSRLEDDGPDDDDDGQRRRKRPKKLTSKEGSDKAGLYQVHPLKIVLHIYDDEIPDTKSLKLVILKFEYLLKLNVVCVGAEGSQDGPEKNIFCNLFPDDAGLEPPHQSTKLILGDGQTFDENRTSRPYKWVQHLAGIDISPVLLGQEAHNTDPAKSDTFVPDLSLYRQQHRVQTVLRRIRLRKKAHLALAEQLDLLMKHELPVVNCEDAPWALHKVLCALDSWLHIQSSASKSCSLTLNSVEQVPEPMEIDVDGRSISGKEDFESIREDGELPSLVTAAASLTSSNHTPSKVSNQARSRQLALMTKNLDSPISKGKSPSFKKYEDDLDLVLDDDSEIDEPTGRTEAHVEELCPEKADNSWVDYGSREFALVFSRKTDGGKLWKLEAMVQISMEYPLRPPLFSLSLHASSSSGNENGTNESDHYNELRAMEAEVNLHMLKIIPSDQENYLLSHQIRCLAMLFDYYVDDPSPDSKRGTATTVVDVGLCKPVDGKLLVRSFRGRDHRKMISWKGRGCASGYPC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
161	Phosphorylation	PEAIKDQSLSSDSSH CHHHHCCCCCCCCCC		19880383
296	Phosphorylation	SRKDSGMSSNTESSR HHHHCCCCCCCCCCC		25561503
297	Phosphorylation	RKDSGMSSNTESSRL HHHCCCCCCCCCCCC		25561503
299	Phosphorylation	DSGMSSNTESSRLED HCCCCCCCCCCCCCC		25561503
609	Phosphorylation	LMTKNLDSPISKGKS HHHCCCCCCCCCCCC		19880383
612	Phosphorylation	KNLDSPISKGKSPSF CCCCCCCCCCCCCCH		25561503
634	Phosphorylation	DLVLDDDSEIDEPTG CEECCCCCCCCCCCC		30291188
640	Phosphorylation	DSEIDEPTGRTEAHV CCCCCCCCCCCCHHH		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of THO5B_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of THO5B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of THO5B_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of THO5B_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.