THO4A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: THO4A_ARATH
• UniProt AC: Q8L773
• Protein Name: THO complex subunit 4A
• Gene Name: ALY1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 244
• Subcellular Localization: Nucleus, nucleoplasm . Nucleus, nucleolus .
• Protein Description: Export adapter involved in nuclear export of spliced and unspliced mRNA..
• Protein Sequence: MSTGLDMSLDDMIAKNRKSRGGAGPARGTGSGSGPGPTRRNNPNRKSTRSAPYQSAKAPESTWGHDMFSDRSEDHRSGRSSAGIETGTKLYISNLDYGVMNEDIKELFAEVGELKRYTVHFDRSGRSKGTAEVVYSRRGDALAAVKKYNDVQLDGKPMKIEIVGTNLQTAAAPSGRPANGNSNGAPWRGGQGRGGQQRGGGRGGGGRGGGGRGRRPGKGPAEKISAEDLDADLDKYHSGDMETN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSTGLDMSL ------CCCCCCCCH		22223895
2	Phosphorylation	------MSTGLDMSL ------CCCCCCCCH		25561503
3	Phosphorylation	-----MSTGLDMSLD -----CCCCCCCCHH		25561503
8	Phosphorylation	MSTGLDMSLDDMIAK CCCCCCCCHHHHHHH		25561503
80	Phosphorylation	EDHRSGRSSAGIETG CCCCCCCCCCCCCCC		25561503
81	Phosphorylation	DHRSGRSSAGIETGT CCCCCCCCCCCCCCC		25561503
241	Sulfoxidation	DKYHSGDMETN---- HHHHCCCCCCC----		23289948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of THO4A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of THO4A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of THO4A_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of THO4A_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.