THIKA_MOUSE - dbPTM
THIKA_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THIKA_MOUSE
UniProt AC Q921H8
Protein Name 3-ketoacyl-CoA thiolase A, peroxisomal
Gene Name Acaa1a
Organism Mus musculus (Mouse).
Sequence Length 424
Subcellular Localization Peroxisome.
Protein Description
Protein Sequence MHRLQVVLGHLAGRPESSSALQAAPCSARFPQASASDVVVVHGRRTPIGRASRGGFKNTTPDELLSAVLTAVLQDVRLKPEQLGDISVGNVLEPGAGAVMARIAQFLSGIPETVPLSTVNRQCSSGLQAVANIAGGIRNGSYDIGMACGVESMSLSGMGNPGNISSRLLESEKARDCLTPMGMTSENVAERFGISRQKQDDFALASQQKAASAQSRGCFRAEIVPVTTTVLDDKGDKKTITVSQDEGVRPSTTMQGLAKLKPAFKDGGSTTAGNSSQVSDGAAAVLLARRSKAEELGLPILGVLRSYAVVGVPPDVMGIGPAYAIPAALQKAGLTVNDIDIFEINEAFASQAVYCVEKLGIPAEKVNPLGGAIALGHPLGCTGARQVVTLLNELKRRGRRAYGVVSMCIGTGMGAAAVFEYPGN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
34PhosphorylationSARFPQASASDVVVV
CCCCCCCCCCCEEEE		24.0623684622
36PhosphorylationRFPQASASDVVVVHG
CCCCCCCCCEEEECC		28.5725521595
52PhosphorylationRTPIGRASRGGFKNT
CCCCCCCCCCCCCCC		30.0523140645
57AcetylationRASRGGFKNTTPDEL
CCCCCCCCCCCHHHH		57.5723954790
79UbiquitinationVLQDVRLKPEQLGDI
HHHHCCCCHHHCCCC		35.6222790023
107UbiquitinationMARIAQFLSGIPETV
HHHHHHHHCCCCCCC		2.8127667366
113PhosphorylationFLSGIPETVPLSTVN
HHCCCCCCCCHHHHH		23.2823140645
117PhosphorylationIPETVPLSTVNRQCS
CCCCCCHHHHHHHHH		25.0023984901
118PhosphorylationPETVPLSTVNRQCSS
CCCCCHHHHHHHHHH		29.5023984901
123S-palmitoylationLSTVNRQCSSGLQAV
HHHHHHHHHHHHHHH		2.9328680068
123S-nitrosylationLSTVNRQCSSGLQAV
HHHHHHHHHHHHHHH		2.9321278135
123S-nitrosocysteineLSTVNRQCSSGLQAV
HHHHHHHHHHHHHHH		2.93-
124PhosphorylationSTVNRQCSSGLQAVA
HHHHHHHHHHHHHHH		21.0723140645
125PhosphorylationTVNRQCSSGLQAVAN
HHHHHHHHHHHHHHH		51.6623140645
140UbiquitinationIAGGIRNGSYDIGMA
HHCCCCCCCCCCCCC		20.1027667366
173AcetylationSRLLESEKARDCLTP
HHHHHCHHHHHCCCC		58.9823576753
173SuccinylationSRLLESEKARDCLTP
HHHHHCHHHHHCCCC		58.9823806337
173MalonylationSRLLESEKARDCLTP
HHHHHCHHHHHCCCC		58.9826320211
177S-palmitoylationESEKARDCLTPMGMT
HCHHHHHCCCCCCCC		3.6728526873
177S-nitrosylationESEKARDCLTPMGMT
HCHHHHHCCCCCCCC		3.6721278135
177GlutathionylationESEKARDCLTPMGMT
HCHHHHHCCCCCCCC		3.6724333276
177S-nitrosocysteineESEKARDCLTPMGMT
HCHHHHHCCCCCCCC		3.67-
179PhosphorylationEKARDCLTPMGMTSE
HHHHHCCCCCCCCCH		19.9825521595
184PhosphorylationCLTPMGMTSENVAER
CCCCCCCCCHHHHHH		27.4529472430
185PhosphorylationLTPMGMTSENVAERF
CCCCCCCCHHHHHHH		20.4829472430
198AcetylationRFGISRQKQDDFALA
HHCCCHHHHCHHHHH		55.3623864654
198UbiquitinationRFGISRQKQDDFALA
HHCCCHHHHCHHHHH		55.3622790023
209UbiquitinationFALASQQKAASAQSR
HHHHHHHHHHHHHHC		37.9822790023
234SuccinylationTTTVLDDKGDKKTIT
EEEEECCCCCCCEEE		69.5424315375
234AcetylationTTTVLDDKGDKKTIT
EEEEECCCCCCCEEE		69.5423576753
237UbiquitinationVLDDKGDKKTITVSQ
EECCCCCCCEEEEEC		61.56-
237AcetylationVLDDKGDKKTITVSQ
EECCCCCCCEEEEEC		61.5623864654
237SuccinylationVLDDKGDKKTITVSQ
EECCCCCCCEEEEEC		61.5624315375
238AcetylationLDDKGDKKTITVSQD
ECCCCCCCEEEEECC		50.317622763
238MalonylationLDDKGDKKTITVSQD
ECCCCCCCEEEEECC		50.3126320211
243PhosphorylationDKKTITVSQDEGVRP
CCCEEEEECCCCCCC		24.2223140645
251PhosphorylationQDEGVRPSTTMQGLA
CCCCCCCCCCHHHHH		26.4146157343
252PhosphorylationDEGVRPSTTMQGLAK
CCCCCCCCCHHHHHH		29.0446157349
253PhosphorylationEGVRPSTTMQGLAKL
CCCCCCCCHHHHHHC		16.3129472430
259AcetylationTTMQGLAKLKPAFKD
CCHHHHHHCCCCCCC		63.1866702263
259UbiquitinationTTMQGLAKLKPAFKD
CCHHHHHHCCCCCCC		63.1827667366
265AcetylationAKLKPAFKDGGSTTA
HHCCCCCCCCCCCCC		58.536566787
269PhosphorylationPAFKDGGSTTAGNSS
CCCCCCCCCCCCCCC		28.2823984901
270PhosphorylationAFKDGGSTTAGNSSQ
CCCCCCCCCCCCCCC		24.7623984901
271PhosphorylationFKDGGSTTAGNSSQV
CCCCCCCCCCCCCCC		33.9723984901
275PhosphorylationGSTTAGNSSQVSDGA
CCCCCCCCCCCCHHH		22.6423984901
276PhosphorylationSTTAGNSSQVSDGAA
CCCCCCCCCCCHHHH		38.3023984901
279PhosphorylationAGNSSQVSDGAAAVL
CCCCCCCCHHHHHHH		23.7723140645
291PhosphorylationAVLLARRSKAEELGL
HHHHHHHHHHHHHCC		30.5722817900
292AcetylationVLLARRSKAEELGLP
HHHHHHHHHHHHCCC		58.99-
292UbiquitinationVLLARRSKAEELGLP
HHHHHHHHHHHHCCC		58.9927667366
323PhosphorylationVMGIGPAYAIPAALQ
CCCCCHHHHHHHHHH		14.277105037
381S-nitrosocysteineALGHPLGCTGARQVV
HHCCCCCCCCHHHHH		4.12-
381GlutathionylationALGHPLGCTGARQVV
HHCCCCCCCCHHHHH		4.1224333276
381S-nitrosylationALGHPLGCTGARQVV
HHCCCCCCCCHHHHH		4.1221278135
389PhosphorylationTGARQVVTLLNELKR
CCHHHHHHHHHHHHH		27.0322817900
395AcetylationVTLLNELKRRGRRAY
HHHHHHHHHCCCCHH		33.592374063
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THIKA_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THIKA_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THIKA_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of THIKA_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THIKA_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory