THADA_MOUSE - dbPTM
THADA_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THADA_MOUSE
UniProt AC A8C756
Protein Name Thyroid adenoma-associated protein homolog
Gene Name Thada
Organism Mus musculus (Mouse).
Sequence Length 1938
Subcellular Localization
Protein Description
Protein Sequence MGVKKKREMQVAALTVCHQDMETLRSFADMEGKNLASLLLHCVQLTDGVSQIHSIKQIVPLLEKVDKNGVCDPAIQSCLDILAGIYFSLTLKNPLKKVLASSLNGLPEVFLTQATHSFTFHLQEELDTADLYSYRKVMDNISSCMENFNLGRASVVNLLKDVLHFLQKSLIEILEENRKFAGNRIVQTQLMSDLLVGVRVAMTLVQKVQGPQGSLWNDSSSPIWQSMCGLLSIFTKFLNDDDLLQTVESTSGLAVILFIKTMFRPSEKLPGLISSLLLRSAECTSIPEWLMNSCRSLCCTDVPASTLLFLCQGTLAMLDWQDGSMGPSGEALLLDIVHVLFTLSSQIKESTLDMFLSRILASWTSSAIQILESGSSGLKGHLNGDSCVPRRLLEYVYTHWEHPLDALRHQTKVMFRNLLQMHRLTMEGADLATDPFCLELTKSLLQLEWHIKGKYACLGCLVETLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRILNYSPESLHYMVHILQASTDTGTGSCNHRGALGALMACLRTARAHGHLQSATQAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMECFTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEPKKSRMDLLKITMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLETVASTVDSELGEPDRHPGMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFIMIDQIPSTLCALLNSLPNSTDQCFRQNHIHGTLLQVFHLLQAYITDCRHRTNADFLQELSDVTACTKAKLWLAMRQNPCLVTRAVYIDILFLLTNCLDRPEEGKQTALESLGFWEDVRRIILESELIKGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAKGQATAVPLSFSRLLKSSFPEVRLLALDTLLERARSSEQEQKEPLPLLCSMGEELLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECYAHLSPKEFLMWSMDIASNDRSEIQGVALKLASKIIAYRVQSCEKNKDSLAPELRQWVQLVVWSCGDHLPTASRLAVAEVLTSTAPLFLTSPQPILELQGTLSLWRCVLTLLQSEEQTVREAATEIVTTAMSQGNTCQSTEFAFCQVDASIALTLALAVLCDLLQQWDQLEPGLPILLGWLLEEGDDLEGHVQSPHQGEEEHIFEKSEVNFWAETLTFVKSLCRQLFHLLCQSGWQSPHSQKLCHLQRIASEQSHLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEGLRAEDCPREWRQVMAPRTEAAC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
15PhosphorylationEMQVAALTVCHQDME
HHHHHHHEECHHHHH
19.1628576409
699PhosphorylationYKLEQRKSTPDSENG
HHHHHCCCCCCCCCC
47.5725338131
858PhosphorylationDALPAVLSASSPQQL
CCCCHHHCCCCCCHH
21.3625777480
860PhosphorylationLPAVLSASSPQQLTR
CCHHHCCCCCCHHHC
38.8929233185
861PhosphorylationPAVLSASSPQQLTRG
CHHHCCCCCCHHHCC
26.8426824392
866PhosphorylationASSPQQLTRGAGETS
CCCCCHHHCCCCCHH
23.7921743459
873PhosphorylationTRGAGETSAVLERNT
HCCCCCHHHHHCHHH
16.4528285833
994PhosphorylationQPRDTNDYFNHTKIL
CCCCCCCCCCHHHHH
14.3529514104
1006PhosphorylationKILKECDSFDLEDLS
HHHHHCCCCCHHHHC
32.1121082442
1013PhosphorylationSFDLEDLSTSVSNID
CCCHHHHCHHHHCCC
30.8425619855
1014PhosphorylationFDLEDLSTSVSNIDS
CCHHHHCHHHHCCCC
40.2125619855
1015PhosphorylationDLEDLSTSVSNIDSS
CHHHHCHHHHCCCCC
21.8525619855
1152PhosphorylationKLCATRRSAGIPFYI
CHHHHHHHCCCCHHH
27.79-
1262AcetylationVFGVKRGKDEVSKTN
HHCCCCCCCHHHHHH
55.5415624017
1729PhosphorylationCVLTLLQSEEQTVRE
HHHHHHHCCHHHHHH
42.9725777480
1733PhosphorylationLLQSEEQTVREAATE
HHHCCHHHHHHHHHH
25.4725777480
1910S-nitrosocysteineAVLRLLACLEGKEGL
HHHHHHHHHHCCCCC
3.42-
1910S-nitrosylationAVLRLLACLEGKEGL
HHHHHHHHHHCCCCC
3.4221278135
1910S-palmitoylationAVLRLLACLEGKEGL
HHHHHHHHHHCCCCC
3.4228526873

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THADA_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THADA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THADA_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of THADA_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THADA_MOUSE

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Related Literatures of Post-Translational Modification

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