UniProt ID | THADA_MOUSE | |
---|---|---|
UniProt AC | A8C756 | |
Protein Name | Thyroid adenoma-associated protein homolog | |
Gene Name | Thada | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 1938 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MGVKKKREMQVAALTVCHQDMETLRSFADMEGKNLASLLLHCVQLTDGVSQIHSIKQIVPLLEKVDKNGVCDPAIQSCLDILAGIYFSLTLKNPLKKVLASSLNGLPEVFLTQATHSFTFHLQEELDTADLYSYRKVMDNISSCMENFNLGRASVVNLLKDVLHFLQKSLIEILEENRKFAGNRIVQTQLMSDLLVGVRVAMTLVQKVQGPQGSLWNDSSSPIWQSMCGLLSIFTKFLNDDDLLQTVESTSGLAVILFIKTMFRPSEKLPGLISSLLLRSAECTSIPEWLMNSCRSLCCTDVPASTLLFLCQGTLAMLDWQDGSMGPSGEALLLDIVHVLFTLSSQIKESTLDMFLSRILASWTSSAIQILESGSSGLKGHLNGDSCVPRRLLEYVYTHWEHPLDALRHQTKVMFRNLLQMHRLTMEGADLATDPFCLELTKSLLQLEWHIKGKYACLGCLVETLGIEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFKNHKSHLKSQTVTNTWMDKWHETWVFPVLSVLCGGNLDQRSYVIDYYLPRILNYSPESLHYMVHILQASTDTGTGSCNHRGALGALMACLRTARAHGHLQSATQAWENLVCSARVKQGLIHQHCQVRIDTLGLLCESNRSTEVVSTEEMQWVQFFITYNLNSQSPGVRQQICSLLKKLFCRIQESSQVLYKLEQRKSTPDSENGSIREQPSVTLQQYKNFMSSVCNILFEALFPGSSYSTRFSALTILGSVAEVFPDPEGNIQTVYQLSHDIDAGRYQILMECFTSTFEEVKTLAFDLLMKLSSVTAGQFQDSEKLQDLFQAALELSTSTKPYDCVTASYLLNLLIRQDALPAVLSASSPQQLTRGAGETSAVLERNTLVVIKCLMENLEDEISQAENSLLQAASSFPMYGRVHCITRAFQRLPLNDLRLASEWRPLLGRLLLLSYRLSTVVAPVIQSSSPEGLIPVDTDSASASRLQLILNEIQPRDTNDYFNHTKILKECDSFDLEDLSTSVSNIDSSAEVKGKEEKACDVTAQMVLACCWRSMKEVALLLGTLCQLLPVQPGPESSNVFLTVQQVKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEILNRCSNVSLQKLPEQWLRSVLEEIKGSDPSSKLCATRRSAGIPFYIQALLASEPKKSRMDLLKITMRELISLALSADDSKGRVPQVHALNILRALFRDTRLGENIIPYVAGGAKAAILGFTSPVWAVRNSSTLLFSSLITRVFGVKRGKDEVSKTNRMTGREFFSRFPELYPFLLKQLETVASTVDSELGEPDRHPGMFLLLLVLERLYPSPMDGTSSALSLAPFVPFIIRCGRSPIYRSREMAARALVPFIMIDQIPSTLCALLNSLPNSTDQCFRQNHIHGTLLQVFHLLQAYITDCRHRTNADFLQELSDVTACTKAKLWLAMRQNPCLVTRAVYIDILFLLTNCLDRPEEGKQTALESLGFWEDVRRIILESELIKGFPWTFKVPGLPQYLQSLTKLAIPEVWASLAEAKGQATAVPLSFSRLLKSSFPEVRLLALDTLLERARSSEQEQKEPLPLLCSMGEELLLLAMKEDHPGCFCRVLKILYHLNPSEWLPQTECYAHLSPKEFLMWSMDIASNDRSEIQGVALKLASKIIAYRVQSCEKNKDSLAPELRQWVQLVVWSCGDHLPTASRLAVAEVLTSTAPLFLTSPQPILELQGTLSLWRCVLTLLQSEEQTVREAATEIVTTAMSQGNTCQSTEFAFCQVDASIALTLALAVLCDLLQQWDQLEPGLPILLGWLLEEGDDLEGHVQSPHQGEEEHIFEKSEVNFWAETLTFVKSLCRQLFHLLCQSGWQSPHSQKLCHLQRIASEQSHLISQLFRELPLSAEFLKTVEYTRLRIQEERTLAVLRLLACLEGKEGLRAEDCPREWRQVMAPRTEAAC | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
15 | Phosphorylation | EMQVAALTVCHQDME HHHHHHHEECHHHHH | 19.16 | 28576409 | |
699 | Phosphorylation | YKLEQRKSTPDSENG HHHHHCCCCCCCCCC | 47.57 | 25338131 | |
858 | Phosphorylation | DALPAVLSASSPQQL CCCCHHHCCCCCCHH | 21.36 | 25777480 | |
860 | Phosphorylation | LPAVLSASSPQQLTR CCHHHCCCCCCHHHC | 38.89 | 29233185 | |
861 | Phosphorylation | PAVLSASSPQQLTRG CHHHCCCCCCHHHCC | 26.84 | 26824392 | |
866 | Phosphorylation | ASSPQQLTRGAGETS CCCCCHHHCCCCCHH | 23.79 | 21743459 | |
873 | Phosphorylation | TRGAGETSAVLERNT HCCCCCHHHHHCHHH | 16.45 | 28285833 | |
994 | Phosphorylation | QPRDTNDYFNHTKIL CCCCCCCCCCHHHHH | 14.35 | 29514104 | |
1006 | Phosphorylation | KILKECDSFDLEDLS HHHHHCCCCCHHHHC | 32.11 | 21082442 | |
1013 | Phosphorylation | SFDLEDLSTSVSNID CCCHHHHCHHHHCCC | 30.84 | 25619855 | |
1014 | Phosphorylation | FDLEDLSTSVSNIDS CCHHHHCHHHHCCCC | 40.21 | 25619855 | |
1015 | Phosphorylation | DLEDLSTSVSNIDSS CHHHHCHHHHCCCCC | 21.85 | 25619855 | |
1152 | Phosphorylation | KLCATRRSAGIPFYI CHHHHHHHCCCCHHH | 27.79 | - | |
1262 | Acetylation | VFGVKRGKDEVSKTN HHCCCCCCCHHHHHH | 55.54 | 15624017 | |
1729 | Phosphorylation | CVLTLLQSEEQTVRE HHHHHHHCCHHHHHH | 42.97 | 25777480 | |
1733 | Phosphorylation | LLQSEEQTVREAATE HHHCCHHHHHHHHHH | 25.47 | 25777480 | |
1910 | S-nitrosocysteine | AVLRLLACLEGKEGL HHHHHHHHHHCCCCC | 3.42 | - | |
1910 | S-nitrosylation | AVLRLLACLEGKEGL HHHHHHHHHHCCCCC | 3.42 | 21278135 | |
1910 | S-palmitoylation | AVLRLLACLEGKEGL HHHHHHHHHHCCCCC | 3.42 | 28526873 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of THADA_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of THADA_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of THADA_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of THADA_MOUSE !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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