dbPTM

TGCE1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TGCE1_SCHPO
UniProt AC	O74430
Protein Name	Probable lipase C1672.09
Gene Name	SPCC1672.09
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	467
Subcellular Localization	Cytoplasm . Membrane Single-pass type II membrane protein .
Protein Description	Probable lipase..
Protein Sequence	MIQLPFIQRLKWEEYMALFLGFFFVIFEKLLSCLAFMIHNTLGLFYRSVVRNEIKKRSKKRSRSRSVSLQRAKAIHDAADIREMCKISGYYVEDHLVRTEDDYILCIHRISKDSPGRIGSPHPKKLPVVYCHHGLLMNSEVWVCNVDPRNCLVFDLVNKGYDVWLGNNRGNKYSRQHLRFDSTDKEFWDFSIDDFAQYDIPDTIDYILKTSGQTKLTYIGFSQGTAQAFASLSIHPLLNDKINSLIALAPAISPKGLHNRVVDAFVKARPSILFFLFGRKSILPSAGFWQSFLAPKFFDAVLAYCLSQLFNWSCQNISSYQRLVSFAHLYSYTSVKCLVHWFQIMRSAEFRMYDNDQLGHDYFLKYYKAAKFPTNNIRTPIYLIWGGSDSLVDIQAMLNALPAEVEHVKVDSYEHLDMIWADTVKDYVIPPVLRRLRDIHHPPEHEENDKENREIQKNHIAPRNKPI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Phosphorylation	RSKKRSRSRSVSLQR HHHHHHHHHCHHHHH	30.10	29996109
66	Phosphorylation	KKRSRSRSVSLQRAK HHHHHHHCHHHHHHH	19.80	28889911
68	Phosphorylation	RSRSRSVSLQRAKAI HHHHHCHHHHHHHHH	21.74	28889911
114	Phosphorylation	IHRISKDSPGRIGSP EEEECCCCCCCCCCC	32.75	24763107
311	N-linked_Glycosylation	YCLSQLFNWSCQNIS HHHHHHHCCCCCCCH	38.04	-
316	N-linked_Glycosylation	LFNWSCQNISSYQRL HHCCCCCCCHHHHHH	40.20	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TGCE1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TGCE1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TGCE1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TGCE1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TGCE1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-66, AND MASSSPECTROMETRY.	18257517 [Abstract]