| UniProt ID | TFPT_MOUSE | |
|---|---|---|
| UniProt AC | Q3U1J1 | |
| Protein Name | TCF3 fusion partner homolog | |
| Gene Name | Tfpt | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 259 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | Appears to promote apoptosis in a p53/TP53-independent manner.; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.. | |
| Protein Sequence | MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETEVEFVSGGLGDSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNRLHQVQRITRRLQQERRFLMRVLDSYGDDYRDSQFTIVLEDDGSQGTDVPTPGNAENEPPEKEGLSPSQRTTATLDPTSPAPGEGPSGRKRRRAPRVGASLTPELAPVQVGAEGWGQGVIKVEEDFGFEADEALDSSWVSREPDKLLPYPTLASPPFD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 68 | Methylation | DEEEEAARGRRRRQR HHHHHHHHHHHHHHH | 46.31 | 16287831 | |
| 148 | Phosphorylation | EDDGSQGTDVPTPGN ECCCCCCCCCCCCCC | 26.62 | 28576409 | |
| 167 | Phosphorylation | PPEKEGLSPSQRTTA CCCCCCCCCHHCCEE | 33.10 | 27087446 | |
| 169 | Phosphorylation | EKEGLSPSQRTTATL CCCCCCCHHCCEEEC | 28.99 | 25159016 | |
| 172 | Phosphorylation | GLSPSQRTTATLDPT CCCCHHCCEEECCCC | 17.10 | 25619855 | |
| 173 | Phosphorylation | LSPSQRTTATLDPTS CCCHHCCEEECCCCC | 21.60 | 25619855 | |
| 175 | Phosphorylation | PSQRTTATLDPTSPA CHHCCEEECCCCCCC | 29.60 | 25619855 | |
| 179 | Phosphorylation | TTATLDPTSPAPGEG CEEECCCCCCCCCCC | 47.19 | 25521595 | |
| 180 | Phosphorylation | TATLDPTSPAPGEGP EEECCCCCCCCCCCC | 25.18 | 26824392 | |
| 188 | Phosphorylation | PAPGEGPSGRKRRRA CCCCCCCCCCCCCCC | 63.19 | 21082442 | |
| 201 (in isoform 2) | Phosphorylation | - | 27.18 | 25159016 | |
| 201 | Phosphorylation | RAPRVGASLTPELAP CCCCCCCCCCCCCCC | 27.18 | 26643407 | |
| 203 (in isoform 2) | Phosphorylation | - | 16.54 | 25159016 | |
| 203 | Phosphorylation | PRVGASLTPELAPVQ CCCCCCCCCCCCCCE | 16.54 | 26643407 | |
| 250 | Phosphorylation | EPDKLLPYPTLASPP CCCCCCCCCCCCCCC | 14.60 | 23984901 | |
| 252 | Phosphorylation | DKLLPYPTLASPPFD CCCCCCCCCCCCCCC | 29.16 | 25159016 | |
| 255 | Phosphorylation | LPYPTLASPPFD--- CCCCCCCCCCCC--- | 35.90 | 24925903 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TFPT_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TFPT_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TFPT_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TFPT_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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