dbPTM

TFE2_XENLA - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TFE2_XENLA
UniProt AC	Q01978
Protein Name	Transcription factor E2-alpha
Gene Name	tcf3
Organism	Xenopus laevis (African clawed frog).
Sequence Length	658
Subcellular Localization	Nucleus .
Protein Description	Transcriptional regulator. Cooperates with MYOD in the activation of cardiac actin gene expression. May ne involved in the initiation of neuronal differentiation. Could be functionally important in muscle gene activation in embryonic development..
Protein Sequence	MNQQQRMTAVGTDKELSDLLDFSMMFPLPVANGKTRPTTLASTQFGGGSGLEERTGSAPWGTEDHNGSTFDQGRGYGDGTHYGEHRELPSHEGNLSAPFLASGLVGKNDRPPYSTFGRDSGMTMNQTGFLSGDLAMNSPSALSPNAGKAGSQYYTYPNNSRRRPGDSNLDAQPKKVRKVPPGLPSSVYPANSGDEYCGDRGSYASTKTPNSVYPGAFYMADGLHSSDIWASSGGIGQGGYSSVLNSSQSSVSQTTGFSSLHPHERMGFPMHSGEVNPSVTSSFSSTPAQYGVSSHTPPISTGDTIIGNRGTATGSSGDALGKALASIYSPDHSSTNFSSTPSTPVGSPQGITGSGQWPRANGPGALSPSYDGTLHTLQNKMEDRLDEAIHVLRSHAVGQTGALPGGHDDIHSLLSATASVLGSGFPAAVLSLANRHSMLNSHTEEALPSASNMLHSQVTVPAQPGSLPDLTRPQDSYSGLPGLGRAIPPGRVPDIKRESKEDEENRSVADLSDDEKKESKPQRSRTRCSINSQDEDEDEDDDNLPPEQKAEREKERRVANNARERLRVKDINEAFKELGRMCQLHLNSEKPQTKLLILHQAVSVILSLEQQVRERNLNPKAACLKRREEEKVSGVDPQMGLSGGHPGVGDSHNPVGHM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of TFE2_XENLA !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TFE2_XENLA !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TFE2_XENLA !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TFE2_XENLA !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
KAISO_XENLA	zbtb33	physical	15935774

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TFE2_XENLA

Related Literatures of Post-Translational Modification