TF3B_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TF3B_SCHPO
• UniProt AC: Q9P6R0
• Protein Name: Transcription factor IIIB 60 kDa subunit
• Gene Name: brf1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 492
• Subcellular Localization: Nucleus .
• Protein Description: General activator of RNA polymerase III transcription..
• Protein Sequence: MGCPNCGSTTFESDTASGNTYCTQCGVVVEQDAIVSEVTFGEASTGAAVVQGSLVSNDQTHARTFGGPYRNQGSVESRELTIANGRRRISALAIALKLNERHIEAAVRYFTLAINNNFIKGRRSQYVVASCLYIVCRISKTSHMLIDFSDILQINVFKLGSTFLKLCRVLRPNLPLLDPSLYISRFASLLEFGPETHRVANDAIRLVARMNRDWMQIGRRPAGICGACLLIAARMNNFRRSVREVVHVVKVADITIQKRLDEFKLTESGDLSIADFRNIWLEGQSDPPSFTKNQKFQQYGAQKVSNIDHTQEYMSPIKRTPDFDGNEVKSEELSQTVKVESQETPVHLKADEREIRKEVTETLKGDELRKISLQVNVKFSEEEVTLEDVDDDEIEDILLDKDEILTKTQVWMELNKDYLAEEEAKNLKLQEDLKKGIVRQPRKRRRYRPRDSTSDGIADTAAESAKEMMQQRAFSKKINYEALDMLFDEEQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
305	Phosphorylation	QYGAQKVSNIDHTQE HHCCEECCCCCCCHH	34.79	29996109
310	Phosphorylation	KVSNIDHTQEYMSPI ECCCCCCCHHHCCCC	21.24	24763107
313	Phosphorylation	NIDHTQEYMSPIKRT CCCCCHHHCCCCCCC	7.96	21712547
315	Phosphorylation	DHTQEYMSPIKRTPD CCCHHHCCCCCCCCC	23.67	24763107
320	Phosphorylation	YMSPIKRTPDFDGNE HCCCCCCCCCCCCCC	23.39	21712547
344	Phosphorylation	VKVESQETPVHLKAD EEEEECCCCCCCCCC	23.99	24763107
452	Phosphorylation	RRYRPRDSTSDGIAD CCCCCCCCCCCCHHH	30.96	29996109
453	Phosphorylation	RYRPRDSTSDGIADT CCCCCCCCCCCHHHH	34.82	25720772
454	Phosphorylation	YRPRDSTSDGIADTA CCCCCCCCCCHHHHH	37.48	29996109
492	Phosphorylation	MLFDEEQS------- HHCCCCCC-------	45.53	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TF3B_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TF3B_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TF3B_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TBP_SCHPO	tbp1	physical	26257282
TFC5_SCHPO	bdp1	physical	26257282
SFC4_SCHPO	sfc4	physical	26257282

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.