TECTB_CHICK - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TECTB_CHICK
• UniProt AC: P54097
• Protein Name: Beta-tectorin
• Gene Name: TECTB
• Organism: Gallus gallus (Chicken).
• Sequence Length: 329
• Subcellular Localization: Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Secreted, extracellular space, extracellular matrix. Found in the non-collagenous matrix of the tectorial membrane..
• Protein Description: One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals..
• Protein Sequence: MVAVTVYLMVILAQAFAGPCTPNKADVILVYCYPRTIITKIPECPYGWEVNQLALGGICYNGIHDSGYYQFTIPDLSPKNKSYCGTQSEFKNPVYHFYNSIVSNDSTVIVKSQPVNYSFTCTYNANYLVNQAAFDQRVATIHVKNGSSGSFESQLSLNFYSNAKFSSIKEAPFVVETSEIGSDIFAGVEAKGLSDRFKVVLNNCWATPSSEYFYQVHWPLITKGCASDFSIVVHENGKTNRATFQFNAFRFQNIPKLSKVWLHCETHVCDSEKFSCPVTCDKRKQRMEQTGGVLVAEISVRNKGLSRFYMLSDVIFHLLFAIGFCAILL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
80	N-linked_Glycosylation	IPDLSPKNKSYCGTQ CCCCCCCCCCCCCCH	41.72	-
104	N-linked_Glycosylation	FYNSIVSNDSTVIVK HHHHHCCCCCEEEEE	36.04	-
116	N-linked_Glycosylation	IVKSQPVNYSFTCTY EEECCCCCEEEEEEE	33.15	-
145	N-linked_Glycosylation	VATIHVKNGSSGSFE EEEEEEECCCCCCEE	55.26	-
304	GPI-anchor	EISVRNKGLSRFYML EEEECCCCCCHHHHH	32.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TECTB_CHICK !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TECTB_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TECTB_CHICK !!

Protein-Protein Interaction

Oops, there are no PPI records of TECTB_CHICK !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.