| UniProt ID | TECT3_MOUSE | |
|---|---|---|
| UniProt AC | Q8R2Q6 | |
| Protein Name | Tectonic-3 | |
| Gene Name | Tctn3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 595 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein . |
|
| Protein Description | Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. May be involved in apoptosis regulation (By similarity). Necessary for signal transduction through the sonic hedgehog (Shh) signaling pathway.. | |
| Protein Sequence | MCTLQLHLLLLVVLMLSETARPQPSSTARAFPTSWGLEPVTPEVPTSAPPDSSESPTPWTLSMPVNATTDPFPALPICVCDLTPGTCDLNCCCDKDCDLLHPRTVFSFCLPGSVRSSSWVCVDNSLMFRSNSPFPSRVFTDSSGTTQFCVRVNNSKANYFQKLQTVNATNFQALAAEFGGQSFPSMPPETQPPVLFYRAGDPILTYYPSWSVVSLLRQPAAVGAGGLCAESNPAGFLESKSTTCPRFFRDLASSCTSEPALDAASYYNFRVLKVPRGVTDLQNMKFQVPVTLASQASPPLLAGNTCQNIVSQVVYEIETNGTFGIQKVSVSFRQTNLTVKPGVSLQQDFIVHFRAFQQRKAAAPAAPRSGNPGYLTGKPLLVLTGDTSHSMTLLQSEGNGLCSAKRHAVQFGVNAVSGCQLRPREVNCSHLQEEVYQTLHGRPRPEHVAVFGNADPAQRGGWTRILSRDCSVSAVNCTSCCLIPVSLEIQVLWAHLGLQSNPQAHVAGARFLYQCKSVQEHQRGIEVSLTTLVNFVDITQKPEPPRDQPRIDWKLPFDFFFPFKAALSRGASVQKDSLVLILCVLLLGLLNSQTK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 167 | N-linked_Glycosylation | FQKLQTVNATNFQAL HHHCCCCCCCCHHHH | 44.42 | - | |
| 253 | Phosphorylation | RFFRDLASSCTSEPA HHHHHHHHHCCCCCC | 32.99 | - | |
| 254 | Phosphorylation | FFRDLASSCTSEPAL HHHHHHHHCCCCCCC | 18.79 | - | |
| 267 | Phosphorylation | ALDAASYYNFRVLKV CCCHHHHCCEEEEEE | 12.82 | - | |
| 336 | N-linked_Glycosylation | SVSFRQTNLTVKPGV EEEEECCCCEECCCC | 25.94 | - | |
| 367 (in isoform 3) | Phosphorylation | - | 32.83 | 25338131 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TECT3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TECT3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TECT3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TECT3_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
