TDR_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TDR_ARATH
• UniProt AC: Q9FII5
• Protein Name: Leucine-rich repeat receptor-like protein kinase TDR
• Gene Name: TDR {ECO:0000303|PubMed:18812507}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1041
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Acts with CLE41p and CLE44p peptides as a ligand-receptor pair in a signal transduction pathway involved in the regulation of procambium maintenance and polarity during vascular-tissue development. Mediates repression of tracheary element differentiation and the promotion of procambial cells formation and polar division adjacent to phloem cells in the veins..
• Protein Sequence: MKKKNISPSLVLHPLLLLLLPFFAFNSLALKFSPQLLSLLSLKTSLSGPPSAFQDWKVPVNGQNDAVWCSWSGVVCDNVTAQVISLDLSHRNLSGRIPIQIRYLSSLLYLNLSGNSLEGSFPTSIFDLTKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNGFTGEIPESYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIPNYVGCKSFYRIELQGNSLNGTIPWDIGHCEKLLCLNLSQNHLNGIIPWEISTLPSIADVDLSHNLLTGTIPSDFGSSKTITTFNVSYNQLIGPIPSGSFAHLNPSFFSSNEGLCGDLVGKPCNSDRFNAGNADIDGHHKEERPKKTAGAIVWILAAAIGVGFFVLVAATRCFQKSYGNRVDGGGRNGGDIGPWKLTAFQRLNFTADDVVECLSKTDNILGMGSTGTVYKAEMPNGEIIAVKKLWGKNKENGKIRRRKSGVLAEVDVLGNVRHRNIVRLLGCCTNRDCTMLLYEYMPNGSLDDLLHGGDKTMTAAAEWTALYQIAIGVAQGICYLHHDCDPVIVHRDLKPSNILLDADFEARVADFGVAKLIQTDESMSVVAGSYGYIAPEYAYTLQVDKKSDIYSYGVILLEIITGKRSVEPEFGEGNSIVDWVRSKLKTKEDVEEVLDKSMGRSCSLIREEMKQMLRIALLCTSRSPTDRPPMRDVLLILQEAKPKRKTVGDNVIVVGDVNDVNFEDVCSVDVGHDVKCQRIGV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
78	N-linked_Glycosylation	WSGVVCDNVTAQVIS CCCEEECCEEEEEEE	28.10	-
92	N-linked_Glycosylation	SLDLSHRNLSGRIPI EEECCCCCCCCCCCH	32.89	-
111	N-linked_Glycosylation	LSSLLYLNLSGNSLE HHHHEEEECCCCCCC	20.71	27055373
258	N-linked_Glycosylation	LKYFDVSNCSLSGSL CCEEECCCCCCCCCC	21.17	27498761
271	N-linked_Glycosylation	SLPQELGNLSNLETL CCCHHHCCCCCCCCE	53.58	27055373
322	N-linked_Glycosylation	SGFSTLKNLTWLSLI CCHHHHHHHHHHHHH	45.90	27449136
332	N-linked_Glycosylation	WLSLISNNLSGEVPE HHHHHHCCCCCCCCC	28.88	-
356	N-linked_Glycosylation	TLFLWNNNFTGVLPH EEEEECCCCCCCCCC	32.42	27055373
378	N-linked_Glycosylation	LETMDVSNNSFTGTI EEEEECCCCCCCCCC	48.27	27055373
430	N-linked_Glycosylation	RSQNNRLNGTIPIGF HHCCCCCCCEEEECC	42.18	27498761
442	N-linked_Glycosylation	IGFGSLRNLTFVDLS ECCCCCCCCEEEECC	49.04	27055373
471	N-linked_Glycosylation	APVLQYLNLSTNFFH HHHHHHHCCCCCCHH	27.32	27055373
525	N-linked_Glycosylation	ELQGNSLNGTIPWDI EEECCCCCCCCCCCH	45.44	27055373
542	N-linked_Glycosylation	CEKLLCLNLSQNHLN HHHEEEEECCCCCCC	36.33	27055373
590	N-linked_Glycosylation	SKTITTFNVSYNQLI CCEEEEEEEECCCEE	21.52	-
710	Phosphorylation	AFQRLNFTADDVVEC EEEECCCCHHHHHHH	28.27	-
798	Phosphorylation	RDCTMLLYEYMPNGS CCCCEEEEEECCCCC	10.89	-
839	Phosphorylation	GVAQGICYLHHDCDP HHHHCHHHHCCCCCC	13.72	-
884	Phosphorylation	IQTDESMSVVAGSYG EECCCCHHHEEECCC	23.79	-
892	Phosphorylation	VVAGSYGYIAPEYAY HEEECCCEECCCEEE	5.91	-
899	Phosphorylation	YIAPEYAYTLQVDKK EECCCEEEEEECCCC	13.69	-
900	Phosphorylation	IAPEYAYTLQVDKKS ECCCEEEEEECCCCC	11.53	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TDR_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TDR_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TDR_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of TDR_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.