TCTP_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCTP_SCHPO
• UniProt AC: Q10344
• Protein Name: Translationally-controlled tumor protein homolog
• Gene Name: p23fy
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 168
• Subcellular Localization: Cytoplasm.
• Protein Description: Involved in calcium binding and microtubule stabilization (By similarity). May be a guanine nucleotide-free chaperone (GFC)..
• Protein Sequence: MLLYKDVISGDELVSDAYDLKEVDDIVYEADCQMVTVKQGGDVDIGANPSAEDAEENAEEGTETVNNLVYSFRLSPTSFDKKSYMSYIKGYMKAIKARLQESNPERVPVFEKNAIGFVKKILANFKDYDFYIGESMDPDAMVVLMNYREDGITPYMIFFKDGLVSEKF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	LLYKDVISGDELVSD CCCCCCCCCCCCCCC	39.79	25720772
78	Phosphorylation	SFRLSPTSFDKKSYM EEEECCCCCCHHHHH	34.53	28889911
165	Phosphorylation	FFKDGLVSEKF---- EECCCCCCCCC----	39.86	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCTP_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCTP_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCTP_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of TCTP_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78, AND MASSSPECTROMETRY.
PubMed: 18257517