TCTA_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCTA_HUMAN
• UniProt AC: P57738
• Protein Name: T-cell leukemia translocation-altered gene protein
• Gene Name: TCTA
• Organism: Homo sapiens (Human).
• Sequence Length: 103
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: May be required for cellular fusion during osteoclastogenesis..
• Protein Sequence: MAESWSGQALQALPATVLGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWEMAANEPLKTHRE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAESWSGQA ------CCCCCCHHH	21.38	25944712
77	N-linked_Glycosylation	RPGLGGQNGSTPDGS CCCCCCCCCCCCCCC	50.05	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCTA_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCTA_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCTA_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TCTA_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.