TCAL5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TCAL5_HUMAN
• UniProt AC: Q5H9L2
• Protein Name: Transcription elongation factor A protein-like 5
• Gene Name: TCEAL5
• Organism: Homo sapiens (Human).
• Sequence Length: 206
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MEKLYKENEGKPENERNLESEGKPEDEGSTEDEGKSDEEEKPDMEGKTECEGKREDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAEDYVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRKKQKMGGFHWMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
30	Phosphorylation	KPEDEGSTEDEGKSD CCCCCCCCCCCCCCC	59.31	25307156
36	Phosphorylation	STEDEGKSDEEEKPD CCCCCCCCCHHHCCC	62.20	24300666
78	Phosphorylation	NQEKQGKSEGEDKPQ CHHCCCCCCCCCCCC	58.62	22468782
92	Phosphorylation	QSEGKPASQAKPESQ CCCCCCHHHCCCCCC	38.92	-
98	Phosphorylation	ASQAKPESQPRAAEK HHHCCCCCCCCHHHH	54.75	25849741
105	Acetylation	SQPRAAEKRPAEDYV CCCCHHHHCCHHHHC	59.98	25953088
105	Ubiquitination	SQPRAAEKRPAEDYV CCCCHHHHCCHHHHC	59.98	24816145
119	Ubiquitination	VPRKAKRKTDRGTDD CCHHHCCCCCCCCCC	54.81	24816145
120	Phosphorylation	PRKAKRKTDRGTDDS CHHHCCCCCCCCCCC	34.65	23403867
124	Phosphorylation	KRKTDRGTDDSPKDS CCCCCCCCCCCCCCC	37.21	29255136
127	Phosphorylation	TDRGTDDSPKDSQED CCCCCCCCCCCCHHH	36.34	29255136
129	Ubiquitination	RGTDDSPKDSQEDLQ CCCCCCCCCCHHHHH	74.16	24816145
131	Phosphorylation	TDDSPKDSQEDLQER CCCCCCCCHHHHHHH	41.41	29255136
141	Phosphorylation	DLQERHLSSEEMMRE HHHHHHCCHHHHHHH	29.58	23401153
142	Phosphorylation	LQERHLSSEEMMREC HHHHHCCHHHHHHHH	43.89	29691806
164	Methylation	EELRKKQKMGGFHWM HHHHHHHHHCCCCCC	48.68	-
182	Methylation	VQDPFAPRGQRGVRG CCCCCCCCCCCCCCC	50.91	16186521
185	Methylation	PFAPRGQRGVRGVRG CCCCCCCCCCCCCCC	48.69	16186529

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TCAL5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TCAL5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TCAL5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TCAL5_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.