TC753_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TC753_ARATH
• UniProt AC: Q9STE8
• Protein Name: Protein TOC75-3, chloroplastic
• Gene Name: TOC75-3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 818
• Subcellular Localization: Plastid, chloroplast outer membrane ; Multi-pass membrane protein .
• Protein Description: Essential protein. Mediates the insertion of proteins targeted to the outer membrane of chloroplasts (By similarity). Required for the import of protein precursors into chloroplasts. Forms the voltage-dependent preprotein translocation channels (hydrophilic beta barrel) of the TOC complex in the chloroplastic outer membrane..
• Protein Sequence: MAAFSVNGQLIPTATSSTASTSLSSRRKFLSPSSSRLPRISTQSPRVPSIKCSKSLPNRDTETSSKDSLLKNLAKPLAVASVSSAASFFLFRISNLPSVLTGGGGGGDGNFGGFGGGGGGGDGNDGGFWGKLFSPSPAVADEEQSPDWDSHGLPANIVVQLNKLSGFKKYKVSDIMFFDRRRQTTIGTEDSFFEMVSIRPGGVYTKAQLQKELETLATCGMFEKVDLEGKTKPDGTLGVTISFAESTWQSADRFRCINVGLMVQSKPIEMDSDMTDKEKLEYYRSLEKDYKRRIDRARPCLLPAPVYGEVMQMLRDQGKVSARLLQRIRDRVQKWYHDEGYACAQVVNFGNLNTKEVVCEVVEGDITQLVIQFQDKLGNVVEGNTQVPVVRRELPKQLRQGYVFNIEAGKKALSNINSLGLFSNIEVNPRPDEKNEGGIIVEIKLKELEQKSAEVSTEWSIVPGRGGAPTLASFQPGGSVTFEHRNLQGLNRSLMGSVTTSNFLNPQDDLSFKLEYVHPYLDGVYNPRNRTFKTSCFNSRKLSPVFTGGPGVEEVPPIWVDRAGVKANITENFTRQSKFTYGLVMEEITTRDESSHIAANGQRLLPSGGISADGPPTTLSGTGVDRMAFLQANITRDNTKFVNGAVVGQRTVFQVDQGLGIGSKFPFFNRHQLTMTKFIQLREVEQGAGKSPPPVLVLHGHYGGCVGDLPSYDAFVLGGPYSVRGYNMGELGAARNIAEVGAEIRIPVKNTHVYAFVEHGNDLGSSKDVKGNPTAVYRRTGQGSSYGAGVKLGLVRAEYAVDHNNGTGALFFRFGERY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	TATSSTASTSLSSRR CCCCCCCCCCHHHCC	20.72	29654922
25	Phosphorylation	TASTSLSSRRKFLSP CCCCCHHHCCCCCCC	41.20	29654922
81	Phosphorylation	AKPLAVASVSSAASF HHHHHHHHHHHHHHH	18.88	25368622
83	Phosphorylation	PLAVASVSSAASFFL HHHHHHHHHHHHHHH	16.27	25368622
84	Phosphorylation	LAVASVSSAASFFLF HHHHHHHHHHHHHHH	26.21	25368622
87	Phosphorylation	ASVSSAASFFLFRIS HHHHHHHHHHHHHHH	19.08	25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TC753_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TC753_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TC753_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of TC753_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.