dbPTM

TBX20_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TBX20_MOUSE
UniProt AC	Q9ES03
Protein Name	T-box transcription factor TBX20
Gene Name	Tbx20
Organism	Mus musculus (Mouse).
Sequence Length	445
Subcellular Localization	Nucleus .
Protein Description	Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart..
Protein Sequence	MEFTASPKPQLSSRANAFSIAALMSSGGPKEKEAAENTIKPLEQFVEKSSCAQPLGELTSLDAHAEFGGGGGSPSSSSLCTEPLIPTTPIIPSEEMAKIACSLETKELWDKFHELGTEMIITKSGRRMFPTIRVSFSGVDPESKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELDQHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGEEDVLGEESQTTQSRGSAFTTSDNLSLSSWVSSSSSFPGFQHPQPLTALGTSTASIATPIPHPIQGSLPPYSRLGMPLTPSAIASSMQGSGPTFPSFHMPRYHHYFQQGPYAAIQGLRHSSAVMTPFV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Phosphorylation	DKFHELGTEMIITKS HHHHHHCCEEEEECC	34.70	22871156
122	Phosphorylation	LGTEMIITKSGRRMF HCCEEEEECCCCCCC	14.29	22871156
131	Phosphorylation	SGRRMFPTIRVSFSG CCCCCCCEEEEEEEC	15.34	22871156
137	Phosphorylation	PTIRVSFSGVDPESK CEEEEEEECCCCCCC	30.33	22871156
143	Phosphorylation	FSGVDPESKYIVLMD EECCCCCCCEEEEEE	35.83	22871156
201	Phosphorylation	QLLKQMVSFEKVKLT HHHHHHHCCEEEECC	23.50	-
311	Phosphorylation	QKHSYARSPIRTYGE HHHCCCCCCCCCCCC	19.26	26824392

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TBX20_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TBX20_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TBX20_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TBX20_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TBX20_MOUSE

Related Literatures of Post-Translational Modification