dbPTM

TBX10_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TBX10_HUMAN
UniProt AC	O75333
Protein Name	T-box transcription factor TBX10
Gene Name	TBX10
Organism	Homo sapiens (Human).
Sequence Length	385
Subcellular Localization	Nucleus .
Protein Description	Probable transcriptional regulator involved in developmental processes..
Protein Sequence	MAAFLSAGLGILAPSETYPLPTTSSGWEPRLGSPFPSGPCTSSTGAQAVAEPTGQGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQVKILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVFVDPRKDSERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRESDLDSWPVAPRPLLSVPARSHSSLSPCVLKGATDREKDPNKASASTSKTPAWLHHQLLPPPEVLLAPATYRPVTYQSLYSGAPSHLGIPRTRPAPYPLPNIRADRDQGGLPLPAGLGLLSPTVVCLGPGQDSQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
154	Phosphorylation	RVHFHPDSPAKGAQW CEEECCCCCCCCHHH	31.07	22210691
167	Phosphorylation	QWMRQIVSFDKLKLT HHHHHHHCCCCCCCC	29.38	22210691
192	Phosphorylation	ILNSMHRYQPRFHVV EECCCHHCCCCEEEE	14.27	-
210	Phosphorylation	PRKDSERYAQENFKS CCCCHHHHHHHHHHH	14.48	-
231	Phosphorylation	QFTAVTAYQNHRITQ CEEEEEEEECCCCEE	10.65	-
237	Phosphorylation	AYQNHRITQLKIASN EEECCCCEEEEEECC	28.01	-
267	Phosphorylation	VAPRPLLSVPARSHS CCCCCCCCCCCCCCC	33.46	-
275	Phosphorylation	VPARSHSSLSPCVLK CCCCCCCCCCCCHHC	27.69	-
277	Phosphorylation	ARSHSSLSPCVLKGA CCCCCCCCCCHHCCC	20.43	-
289	Ubiquitination	KGATDREKDPNKASA CCCCCCCCCCCCCCC	78.40	32015554

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TBX10_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TBX10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TBX10_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TBX10_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TBX10_HUMAN

Related Literatures of Post-Translational Modification