TBCEL_HUMAN - dbPTM
TBCEL_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TBCEL_HUMAN
UniProt AC Q5QJ74
Protein Name Tubulin-specific chaperone cofactor E-like protein
Gene Name TBCEL
Organism Homo sapiens (Human).
Sequence Length 424
Subcellular Localization Cytoplasm, cytoskeleton .
Protein Description Acts as a regulator of tubulin stability..
Protein Sequence MDQPSGRSFMQVLCEKYSPENFPYRRGPGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNKLEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNNSKASWETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANNHLNAIEEPDDSLARLFPNLRSISLHKSGLQSWEDIDKLNSFPKLEEVRLLGIPLLQPYTTEERRKLVIARLPSVSKLNGSVVTDGEREDSERFFIRYYVDVPQEEVPFRYHELITKYGKLEPLAEVDLRPQSSAKVEVHFNDQVEEMSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFGPEEMKYSSRALHSFGIRDGDKIYVESKTK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
17PhosphorylationMQVLCEKYSPENFPY
HHHHHHHCCCCCCCC
13.7327732954
18PhosphorylationQVLCEKYSPENFPYR
HHHHHHCCCCCCCCC
36.4827732954
37PhosphorylationMGVHVPATPQGSPMK
CCCCCCCCCCCCCCC
15.2929255136
41PhosphorylationVPATPQGSPMKDRLN
CCCCCCCCCCCCCCC
19.3029255136
77PhosphorylationAAFCAHVSELDLSDN
HHHHEEHHHCCCCCC
23.6829759185
82PhosphorylationHVSELDLSDNKLEDW
EHHHCCCCCCCCCCH
38.5129759185
130UbiquitinationGSFSGVRKLVLNNSK
CCCCCCEEHHHCCCC
40.3129967540
236UbiquitinationLRSISLHKSGLQSWE
CCCEEECCCCCCCHH
52.0622817900
241PhosphorylationLHKSGLQSWEDIDKL
ECCCCCCCHHHHHHH
37.1630622161
247UbiquitinationQSWEDIDKLNSFPKL
CCHHHHHHHHCCCCH
50.3229967540
283PhosphorylationLVIARLPSVSKLNGS
HHEEECCCHHHCCCE
43.5529514088
285PhosphorylationIARLPSVSKLNGSVV
EEECCCHHHCCCEEE
35.4429514088
326UbiquitinationRYHELITKYGKLEPL
CHHHHHHHHCCEEEC
45.0429967540
329UbiquitinationELITKYGKLEPLAEV
HHHHHHCCEEECEEC
46.7329967540
342PhosphorylationEVDLRPQSSAKVEVH
ECCCCCCCCCEEEEE
34.6425850435
343PhosphorylationVDLRPQSSAKVEVHF
CCCCCCCCCEEEEEE
27.1925850435
364PhosphorylationMSIRLDQTVAELKKQ
HHHHHHHHHHHHHHH
22.73-
401PhosphorylationFGPEEMKYSSRALHS
CCHHHHCCCHHHHHH
15.5724719451
408PhosphorylationYSSRALHSFGIRDGD
CCHHHHHHCCCCCCC
26.4724719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TBCEL_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TBCEL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TBCEL_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TBCEL_HUMAN !!

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TBCEL_HUMAN

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Related Literatures of Post-Translational Modification

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