TBCD9_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TBCD9_MOUSE
• UniProt AC: Q3UYK3
• Protein Name: TBC1 domain family member 9
• Gene Name: Tbc1d9
• Organism: Mus musculus (Mouse).
• Sequence Length: 1264
• Protein Description: May act as a GTPase-activating protein for Rab family protein(s)..
• Protein Sequence: MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDVTTFVRGKIQGIIAEYNKINDVKEDEDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGRVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDMIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDKEFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEGLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSCDQDEPDSAFEATQYFFEDITPECTHVVGLDSRGKQSADDGFVTVSLKQDRGKRANSQENRNYLKLWTAENKSKSKTAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPAKEDAVPGPPCGQAIPGMLFPKKGSSQSYVVESTEPLTASLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGRATLPRSSSLDRDWAITFEQFLASLLTEPALVRYFDKPVCMMARVTSAKNIRMMGKPLTSASDYEISALSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
267	Phosphorylation	EGFEQDRSLPKLKKK CCCCCCCCCCHHCCC	58.26	22942356
396	Phosphorylation	DFLVQRISDFLQQTT HHHHHHHHHHHHHHH	25.21	22817900
402	Phosphorylation	ISDFLQQTTSRIYSD HHHHHHHHHHHCCCC	17.49	-
404	Phosphorylation	DFLQQTTSRIYSDKE HHHHHHHHHCCCCCC	21.77	22817900
418	Phosphorylation	EFSGSCNSSDDEVYS CCCCCCCCCCCCCCC	39.20	29899451
419	Phosphorylation	FSGSCNSSDDEVYSR CCCCCCCCCCCCCCC	34.78	29899451
424	Phosphorylation	NSSDDEVYSRPSSLV CCCCCCCCCCCHHHC	9.27	29899451
432	Phosphorylation	SRPSSLVSSSPQRST CCCHHHCCCCCCCCC	30.32	20415495
433	Phosphorylation	RPSSLVSSSPQRSTS CCHHHCCCCCCCCCC	38.26	29899451
434	Phosphorylation	PSSLVSSSPQRSTSS CHHHCCCCCCCCCCC	19.97	25521595
438	Phosphorylation	VSSSPQRSTSSDADG CCCCCCCCCCCCCCC	27.65	-
441	Phosphorylation	SPQRSTSSDADGERP CCCCCCCCCCCCCCC	36.59	-
471	Phosphorylation	MTMYRRRSPEEFNPK HHHHHHCCHHHHCHH	34.55	26824392
1150	Phosphorylation	ACSSMLISDDDTKDD CCCCEEECCCCCCCC	30.90	25521595
1196	Phosphorylation	RSSQGRATLPRSSSL ECCCCCCCCCCCCCC	35.61	24719451
1240	Phosphorylation	CMMARVTSAKNIRMM EEEEEECCHHCCCCC	34.10	23140645
1255	Phosphorylation	GKPLTSASDYEISAL CCCCCCCCHHCHHHC	40.26	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TBCD9_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TBCD9_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TBCD9_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TBCD9_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.