TBC26_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TBC26_HUMAN
• UniProt AC: Q86UD7
• Protein Name: TBC1 domain family member 26
• Gene Name: TBC1D26
• Organism: Homo sapiens (Human).
• Sequence Length: 250
• Protein Description: May act as a GTPase-activating protein for Rab family protein(s)..
• Protein Sequence: MEMDGDPYNLPAQGQGNIIITKYEQGHRAGAAVDLGHEQVDVRKYTNNLGIVHEMELPHVSALEVKQRRKESKRTNKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKGKRSSRIIHCIQLDVSHTLQKHMMFIQRFGVKQQELCDILVAYSAYNPEVGYHRDLSRITAILLLCLPEEDAFWALTQLLAGERHSLWYSTAQILPGSRGSYRTRSRCCTSPSQRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Phosphorylation	EQVDVRKYTNNLGIV CEEEHHHHHCCCCCC	12.25	28787133
46	Phosphorylation	QVDVRKYTNNLGIVH EEEHHHHHCCCCCCE	22.21	28787133
87	Acetylation	KMLADWTKYRSTKKL HHHHHHHHHCCCHHH	34.12	30586357
92	Methylation	WTKYRSTKKLSQRVY HHHHCCCHHHHHHHH	53.62	-
112	O-linked_Glycosylation	AVRGRAWSLLLDIDR HHCHHHHHHHHCHHH	14.25	30620550
150	Phosphorylation	HCIQLDVSHTLQKHM EEEECCCHHHHHHHH	15.49	26074081
152	Phosphorylation	IQLDVSHTLQKHMMF EECCCHHHHHHHHHH	24.31	26074081
223	Phosphorylation	GERHSLWYSTAQILP CCCCHHHHCCCEECC	11.05	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TBC26_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TBC26_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TBC26_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TBC26_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.