| UniProt ID | TBAL3_MOUSE | |
|---|---|---|
| UniProt AC | Q3UX10 | |
| Protein Name | Tubulin alpha chain-like 3 | |
| Gene Name | Tubal3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 446 | |
| Subcellular Localization | Cytoplasm, cytoskeleton. | |
| Protein Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).. | |
| Protein Sequence | MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFFHETRAGKHVPRTLFMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLAEQCSGLQGFLIYRSFGGGTGSGFTSLLMERLSVEYCKKIKLEFSVYPSPRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYDICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEEVGLSF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 90 | Phosphorylation | DGIRVGRYHSLFHPE CCEEECCCCCCCCHH | 6.99 | 30165576 | |
| 92 | Phosphorylation | IRVGRYHSLFHPEQL EEECCCCCCCCHHHH | 24.64 | 30165576 | |
| 248 | Phosphorylation | VSSSITASLRFEGPL HHCCHHEEEEECCCC | 16.07 | 22802335 | |
| 270 | Ubiquitination | QTNLVPYPRIHFPIT ECCCCCCCCCCCCHH | 23.76 | 27667366 | |
| 281 | Ubiquitination | FPITALAPIISAEKA CCHHHHHHHHCHHHH | 25.87 | 27667366 | |
| 284 | Phosphorylation | TALAPIISAEKAYQE HHHHHHHCHHHHHHH | 30.97 | 25177544 | |
| 323 | S-nitrosylation | LGKYMACCLLYRGDV HHHHHHHHHHHCCCC | 1.81 | 24926564 | |
| 326 | Phosphorylation | YMACCLLYRGDVVPK HHHHHHHHCCCCCCC | 10.29 | 18034455 | |
| 401 | Ubiquitination | AWARLDHKFDLMYAK HHHHCCCHHHHHHHH | 39.99 | 22790023 | |
| 406 | Phosphorylation | DHKFDLMYAKKAFLH CCHHHHHHHHHHHHH | 23.67 | 26745281 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TBAL3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TBAL3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TBAL3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TBAL3_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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