dbPTM

TB1RA_XENLA - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TB1RA_XENLA
UniProt AC	Q7SZM9
Protein Name	F-box-like/WD repeat-containing protein TBL1XR1-A
Gene Name	tbl1xr1-a
Organism	Xenopus laevis (African clawed frog).
Sequence Length	519
Subcellular Localization	Nucleus.
Protein Description	F-box-like protein which acts as an integral component of the N-CoR transcriptional corepressor complex. Probably regulates transcription activation mediated by nuclear receptors. May mediate the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of the N-CoR complex, thereby allowing cofactor exchange and transcription activation (By similarity)..
Protein Sequence	MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALAPPAALISIIQKGLQYVEAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQTAAAAAAAAAAAATPNNQQPPAKNGENTANGEENGGHALANNHTDMMEVDGDVEIPSSKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKHDTCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of TB1RA_XENLA !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TB1RA_XENLA !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TB1RA_XENLA !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TB1RA_XENLA !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
NCOR1_XENLA	ncor1	physical	15060155

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TB1RA_XENLA

Related Literatures of Post-Translational Modification