TALDO_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TALDO_RAT
• UniProt AC: Q9EQS0
• Protein Name: Transaldolase
• Gene Name: Taldo1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 337
• Subcellular Localization: Cytoplasm .
• Protein Description: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway..
• Protein Sequence: MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRIIELYKEAGISKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDSSKLAPTLSVKAAQTSDLEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGSPVKRQ ------CCCCHHHHH	48.23	22673903
4	Phosphorylation	----MSGSPVKRQRM ----CCCCHHHHHHH	21.15	22673903
7	Acetylation	-MSGSPVKRQRMESA -CCCCHHHHHHHHHH	46.31	22902405
115	Acetylation	DARLSFDKDAMVARA CHHHCCCHHHHHHHH	45.43	-
130	Acetylation	RRIIELYKEAGISKD HHHHHHHHHHCCCCC	54.43	22902405
130	Ubiquitination	RRIIELYKEAGISKD HHHHHHHHHHCCCCC	54.43	-
136	Acetylation	YKEAGISKDRILIKL HHHHCCCCCCEEEEE	49.45	22902405
203	Acetylation	WHVANTDKKSYEPQE HHHCCCCCCCCCCCC	41.39	22902405
205	Phosphorylation	VANTDKKSYEPQEDP HCCCCCCCCCCCCCC	40.23	30181290
206	Phosphorylation	ANTDKKSYEPQEDPG CCCCCCCCCCCCCCC	40.27	30181290
219	Acetylation	PGVKSVTKIYNYYKK CCCCHHHHHHHHHHH	40.83	22902405
219	Ubiquitination	PGVKSVTKIYNYYKK CCCCHHHHHHHHHHH	40.83	-
237	Phosphorylation	KTIVMGASFRNTGEI CEEEECCCCCCCCHH	21.00	28689409
241	Phosphorylation	MGASFRNTGEIKALA ECCCCCCCCHHHHHC	31.75	23984901
254	Phosphorylation	LAGCDFLTISPKLLG HCCCCEEEECHHHHH	21.28	23984901
256	Phosphorylation	GCDFLTISPKLLGEL CCCEEEECHHHHHHH	15.67	23984901
258	Ubiquitination	DFLTISPKLLGELLK CEEEECHHHHHHHHC	49.94	-
258	Acetylation	DFLTISPKLLGELLK CEEEECHHHHHHHHC	49.94	25786129
265	Acetylation	KLLGELLKDSSKLAP HHHHHHHCCCCCCCC	69.09	22902405
267	Phosphorylation	LGELLKDSSKLAPTL HHHHHCCCCCCCCCC	27.99	29779826
268	Phosphorylation	GELLKDSSKLAPTLS HHHHCCCCCCCCCCC	41.65	25575281
269	Acetylation	ELLKDSSKLAPTLSV HHHCCCCCCCCCCCC	53.25	22902405
269	Ubiquitination	ELLKDSSKLAPTLSV HHHCCCCCCCCCCCC	53.25	-
273	Phosphorylation	DSSKLAPTLSVKAAQ CCCCCCCCCCCEECC	26.51	25575281
275	Phosphorylation	SKLAPTLSVKAAQTS CCCCCCCCCEECCCC	24.85	25575281
277	Ubiquitination	LAPTLSVKAAQTSDL CCCCCCCEECCCCCH	34.33	-
286	Acetylation	AQTSDLEKIHLDEKA CCCCCHHHHCCCHHH	42.60	25786129
292	Acetylation	EKIHLDEKAFRWLHN HHHCCCHHHHHHHHC	53.11	22902405
307	Acetylation	EDQMAVEKLSDGIRK HHHHHHHHHHHHHHH	46.85	22902405
314	Acetylation	KLSDGIRKFAADAIK HHHHHHHHHHHHHHH	37.12	25786129
321	Acetylation	KFAADAIKLERMLTE HHHHHHHHHHHHHHH	46.12	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TALDO_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TALDO_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TALDO_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of TALDO_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS.";
Moser K., White F.M.;
J. Proteome Res. 5:98-104(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-237, AND MASSSPECTROMETRY.
PubMed: 16396499