TALDO_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TALDO_MOUSE
• UniProt AC: Q93092
• Protein Name: Transaldolase
• Gene Name: Taldo1
• Organism: Mus musculus (Mouse).
• Sequence Length: 337
• Subcellular Localization: Cytoplasm .
• Protein Description: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway..
• Protein Sequence: MSGSPVKRQRMESALDQLKQFTTVVADTGDFNAIDEYKPQDATTNPSLILAAAQMPAYQELVEEAIAYGKKLGGPQEEQIKNAIDKLFVLFGAEILKKIPGRVSTEVDARLSFDKDAMVARARRLIELYKEAGVGKDRILIKLSSTWEGIQAGKELEEQHGIHCNMTLLFSFAQAVACAEAGVTLISPFVGRILDWHVANTDKKSYEPQEDPGVKSVTKIYNYYKKFGYKTIVMGASFRNTGEIKALAGCDFLTISPKLLGELLKDNSKLAPALSVKAAQTSDSEKIHLDEKAFRWLHNEDQMAVEKLSDGIRKFAADAIKLERMLTERMFSAENGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGSPVKRQ ------CCCCHHHHH	48.23	21743459
4	Phosphorylation	----MSGSPVKRQRM ----CCCCHHHHHHH	21.15	26824392
7	Malonylation	-MSGSPVKRQRMESA -CCCCHHHHHHHHHH	46.31	26320211
71	Ubiquitination	EAIAYGKKLGGPQEE HHHHHHHHCCCCHHH	48.26	22790023
81	Ubiquitination	GPQEEQIKNAIDKLF CCHHHHHHHHHHHHH	39.77	22790023
86	Acetylation	QIKNAIDKLFVLFGA HHHHHHHHHHHHHCH	37.40	22826441
115	Ubiquitination	DARLSFDKDAMVARA HHHHCCCHHHHHHHH	45.43	22790023
115	Acetylation	DARLSFDKDAMVARA HHHHCCCHHHHHHHH	45.43	23806337
130	Acetylation	RRLIELYKEAGVGKD HHHHHHHHHHCCCCC	54.43	22826441
130	Malonylation	RRLIELYKEAGVGKD HHHHHHHHHHCCCCC	54.43	26320211
130	Ubiquitination	RRLIELYKEAGVGKD HHHHHHHHHHCCCCC	54.43	27667366
136	Acetylation	YKEAGVGKDRILIKL HHHHCCCCCEEEEEE	41.23	23954790
138	Methylation	EAGVGKDRILIKLSS HHCCCCCEEEEEECC	29.15	30989467
142	Acetylation	GKDRILIKLSSTWEG CCCEEEEEECCCCCH	38.58	22826441
203	Ubiquitination	WHVANTDKKSYEPQE HHHCCCCCCCCCCCC	41.39	22790023
204	Sumoylation	HVANTDKKSYEPQED HHCCCCCCCCCCCCC	62.17	28289178
204	Acetylation	HVANTDKKSYEPQED HHCCCCCCCCCCCCC	62.17	22826441
204	Ubiquitination	HVANTDKKSYEPQED HHCCCCCCCCCCCCC	62.17	27667366
204	Malonylation	HVANTDKKSYEPQED HHCCCCCCCCCCCCC	62.17	26320211
205	Phosphorylation	VANTDKKSYEPQEDP HCCCCCCCCCCCCCC	40.23	23684622
206	Phosphorylation	ANTDKKSYEPQEDPG CCCCCCCCCCCCCCC	40.27	21082442
215	Ubiquitination	PQEDPGVKSVTKIYN CCCCCCCCHHHHHHH	45.16	22790023
219	Ubiquitination	PGVKSVTKIYNYYKK CCCCHHHHHHHHHHH	40.83	22790023
219	Acetylation	PGVKSVTKIYNYYKK CCCCHHHHHHHHHHH	40.83	22826441
225	Succinylation	TKIYNYYKKFGYKTI HHHHHHHHHHCCCEE	31.13	23954790
225	Acetylation	TKIYNYYKKFGYKTI HHHHHHHHHHCCCEE	31.13	22826441
226	Acetylation	KIYNYYKKFGYKTIV HHHHHHHHHCCCEEE	28.09	7618083
230	Acetylation	YYKKFGYKTIVMGAS HHHHHCCCEEEECCC	31.96	22826441
231	Phosphorylation	YKKFGYKTIVMGASF HHHHCCCEEEECCCC	15.43	23527152
237	Phosphorylation	KTIVMGASFRNTGEI CEEEECCCCCCCCHH	21.00	23527152
241	Phosphorylation	MGASFRNTGEIKALA ECCCCCCCCHHHHHC	31.75	23984901
245	Acetylation	FRNTGEIKALAGCDF CCCCCHHHHHCCCCE	32.80	22826441
250	Glutathionylation	EIKALAGCDFLTISP HHHHHCCCCEEEECH	2.52	24333276
250	S-nitrosylation	EIKALAGCDFLTISP HHHHHCCCCEEEECH	2.52	21278135
250	S-nitrosocysteine	EIKALAGCDFLTISP HHHHHCCCCEEEECH	2.52	-
254	Phosphorylation	LAGCDFLTISPKLLG HCCCCEEEECHHHHH	21.28	22324799
256	Phosphorylation	GCDFLTISPKLLGEL CCCEEEECHHHHHHH	15.67	26643407
258	Acetylation	DFLTISPKLLGELLK CEEEECHHHHHHHHC	49.94	22733758
258	Ubiquitination	DFLTISPKLLGELLK CEEEECHHHHHHHHC	49.94	-
258	Malonylation	DFLTISPKLLGELLK CEEEECHHHHHHHHC	49.94	26073543
265	Malonylation	KLLGELLKDNSKLAP HHHHHHHCCCCCCCC	68.44	26320211
265	Acetylation	KLLGELLKDNSKLAP HHHHHHHCCCCCCCC	68.44	22826441
265	Ubiquitination	KLLGELLKDNSKLAP HHHHHHHCCCCCCCC	68.44	27667366
268	Phosphorylation	GELLKDNSKLAPALS HHHHCCCCCCCCCCC	38.90	22817900
269	Acetylation	ELLKDNSKLAPALSV HHHCCCCCCCCCCCC	55.72	23236377
269	Malonylation	ELLKDNSKLAPALSV HHHCCCCCCCCCCCC	55.72	26320211
269	Ubiquitination	ELLKDNSKLAPALSV HHHCCCCCCCCCCCC	55.72	27667366
275	Phosphorylation	SKLAPALSVKAAQTS CCCCCCCCCEEECCC	24.55	29176673
277	Ubiquitination	LAPALSVKAAQTSDS CCCCCCCEEECCCCC	34.33	22790023
286	Acetylation	AQTSDSEKIHLDEKA ECCCCCCCCCCCHHH	39.10	23806337
286	Ubiquitination	AQTSDSEKIHLDEKA ECCCCCCCCCCCHHH	39.10	-
286	Malonylation	AQTSDSEKIHLDEKA ECCCCCCCCCCCHHH	39.10	26320211
292	Acetylation	EKIHLDEKAFRWLHN CCCCCCHHHHHHHHC	53.11	22826441
292	Ubiquitination	EKIHLDEKAFRWLHN CCCCCCHHHHHHHHC	53.11	22790023
307	Acetylation	EDQMAVEKLSDGIRK HHHHHHHHHHHHHHH	46.85	23236377
307	Ubiquitination	EDQMAVEKLSDGIRK HHHHHHHHHHHHHHH	46.85	22790023
314	Phosphoglycerylation	KLSDGIRKFAADAIK HHHHHHHHHHHHHHH	37.12	-
314	Malonylation	KLSDGIRKFAADAIK HHHHHHHHHHHHHHH	37.12	26320211
314	Ubiquitination	KLSDGIRKFAADAIK HHHHHHHHHHHHHHH	37.12	27667366
321	Malonylation	KFAADAIKLERMLTE HHHHHHHHHHHHHHH	46.12	26073543
321	Acetylation	KFAADAIKLERMLTE HHHHHHHHHHHHHHH	46.12	23806337
321	Ubiquitination	KFAADAIKLERMLTE HHHHHHHHHHHHHHH	46.12	27667366
337	Acetylation	MFSAENGK------- HHCCCCCC-------	69.61	61251

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TALDO_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TALDO_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TALDO_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TALDO_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.